AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF

The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO3Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and ma...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	PILLAI, BIJUKUMAR GOPINATHAN, RAMAN, JAYARAMAN, VENKAT, PATEL, HITESH, DHAMELIYA, DHARMESH, JINJALA, GOVIND, BALAJI, SUNDARA KALYANA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES THEIR PREPARATION OR CHEMICAL WORKING-UP
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO3Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and magnesium which provides in particular to a narrow distribution low molecular weight, highly sulfated Pentosan polysulfate (in this instance a Xylan). Cette invention concerne un procédé de préparation amélioré de polysulfate de pentosane de formule (I) ou de son sel. Dans la formule (I), R représente -SO3Y, et Y est au moins un élément choisi dans le groupe constitué par H et un cation de qualité pharmaceutique tel que sodium, potassium, et magnésium qui donne, en particulier, un polysulfate de pentosane très sulfaté (dans ce cas, xylane), de bas poids moléculaire et distribution étroite.