DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS

The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions fo...

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Bibliographische Detailangaben
Hauptverfasser:	THENNATI, RAJAMANNAR, SENGUPTA, PRABAL, CHITTURI, TRINADHA RAO, PURI, CHETAN SURJITSINGH, DESAI, DIPALI MANUBHAI, CHIMANWALA, SABBIRHUSEN YUSUFBHAI, MEHTA, VARUN ANILKUMAR, ATKINSON, JONATHAN DAVID MARK, CHOKSHI, HEMANT ASHVINBHAI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to tyrosine kinases, in warm-blooded animals La présente invention concerne de nouveaux composés diarylacétylène hydrazide de formule (I) ou un sel pharmaceutiquement acceptable de ceux-ci, en tant qu'inhibiteurs de tyrosine kinase, leur procédé de préparation et l'utilisation des composés de formule (I) dans la préparation de compositions pharmaceutiques pour le traitement thérapeutique de troubles associés à des tyrosine kinase, chez les animaux à sang chaud.