A NOVEL POLYMORPHIC FORM OF RIFAXIMIN AND PROCESS FOR ITS PREPARATION

A NOVEL POLYMORPHIC FORM OF RIFAXIMIN AND PROCESS FOR ITS PREPARATION

The present invention discloses a stable amorphous form of Rifaximin characterised by having X-ray powder diffraction pattern as given in figure 1, having a 2? peaks at 7.2 and having moisture content in the range of 3% to 4% preferably, 3.4% to 3.7%. This invention also discloses a novel process fo...

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Hauptverfasser: MADATHIL, VIJESH ALANTHATTA, ARULMOLI, THANGAVEL, VASUDEVA, PEJAKALA KAKRANNAYA, VENKATRAMANA, SUMANGALA
Format: Patent
Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator MADATHIL, VIJESH ALANTHATTA
ARULMOLI, THANGAVEL
VASUDEVA, PEJAKALA KAKRANNAYA
VENKATRAMANA, SUMANGALA
description The present invention discloses a stable amorphous form of Rifaximin characterised by having X-ray powder diffraction pattern as given in figure 1, having a 2? peaks at 7.2 and having moisture content in the range of 3% to 4% preferably, 3.4% to 3.7%. This invention also discloses a novel process for its preparation. La présente invention concerne une forme amorphe stable de rifaximine caractérisée en ce qu'elle présente un diagramme de diffraction des rayons X sur poudre tel qu'illustré dans la figure 1, présentant un pic 2? à 7,2 et présentant une teneur en humidité comprise dans la plage de 3% à 4% et préférablement, de 3,4% à 3,7%. L'invention concerne également un nouveau procédé de préparation de ladite forme.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title A NOVEL POLYMORPHIC FORM OF RIFAXIMIN AND PROCESS FOR ITS PREPARATION
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