METHOD OF DETECTING TAU PROTEIN AND TAU FRAGMENTS IN SERUM
The present invention provides quantitative methods for the detection of tau protein and/or tau fragments. More specifically, the present invention provides quantitative methods for diagnosing a tauopathy or ruling out a tauopathy as the cause of disease, particularly the diagnosis and ruling of Alz...
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| creator | DEBERNARDIS, JOHN, F ZINKOWSKI, RAYMOND, P |
| description | The present invention provides quantitative methods for the detection of tau protein and/or tau fragments. More specifically, the present invention provides quantitative methods for diagnosing a tauopathy or ruling out a tauopathy as the cause of disease, particularly the diagnosis and ruling of Alzheimer's disease. The present invention further provides a method for diagnosing a tauopathy by computing the ratio of two detected tau proteins or tau fragments.
La présente invention concerne des procédés quantitatifs pour la détection de la protéine tau et/ou de fragments de tau. De façon plus spécifique, la présente invention porte sur des procédés quantitatifs pour le diagnostic d'une tauopathie ou pour écarter une tauopathie en tant que cause de maladie, en particulier, le diagnostic et l'élimination de la maladie d'Alzheimer. La présente invention porte en outre sur un procédé de diagnostic d'une tauopathie par le calcul du rapport de deux protéines tau ou fragments de tau détectés. |
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La présente invention concerne des procédés quantitatifs pour la détection de la protéine tau et/ou de fragments de tau. De façon plus spécifique, la présente invention porte sur des procédés quantitatifs pour le diagnostic d'une tauopathie ou pour écarter une tauopathie en tant que cause de maladie, en particulier, le diagnostic et l'élimination de la maladie d'Alzheimer. La présente invention porte en outre sur un procédé de diagnostic d'une tauopathie par le calcul du rapport de deux protéines tau ou fragments de tau détectés.</description><language>eng ; fre</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110909&DB=EPODOC&CC=WO&NR=2011109112A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110909&DB=EPODOC&CC=WO&NR=2011109112A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DEBERNARDIS, JOHN, F</creatorcontrib><creatorcontrib>ZINKOWSKI, RAYMOND, P</creatorcontrib><title>METHOD OF DETECTING TAU PROTEIN AND TAU FRAGMENTS IN SERUM</title><description>The present invention provides quantitative methods for the detection of tau protein and/or tau fragments. More specifically, the present invention provides quantitative methods for diagnosing a tauopathy or ruling out a tauopathy as the cause of disease, particularly the diagnosis and ruling of Alzheimer's disease. The present invention further provides a method for diagnosing a tauopathy by computing the ratio of two detected tau proteins or tau fragments.
La présente invention concerne des procédés quantitatifs pour la détection de la protéine tau et/ou de fragments de tau. De façon plus spécifique, la présente invention porte sur des procédés quantitatifs pour le diagnostic d'une tauopathie ou pour écarter une tauopathie en tant que cause de maladie, en particulier, le diagnostic et l'élimination de la maladie d'Alzheimer. La présente invention porte en outre sur un procédé de diagnostic d'une tauopathie par le calcul du rapport de deux protéines tau ou fragments de tau détectés.</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDydQ3x8HdR8HdTcHENcXUO8fRzVwhxDFUICPIPcfX0U3D0cwHz3YIc3X1d_UKCFYCCwa5Bob48DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IwNDQ0MDS0NDI0ciYOFUANRkplg</recordid><startdate>20110909</startdate><enddate>20110909</enddate><creator>DEBERNARDIS, JOHN, F</creator><creator>ZINKOWSKI, RAYMOND, P</creator><scope>EVB</scope></search><sort><creationdate>20110909</creationdate><title>METHOD OF DETECTING TAU PROTEIN AND TAU FRAGMENTS IN SERUM</title><author>DEBERNARDIS, JOHN, F ; ZINKOWSKI, RAYMOND, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2011109112A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2011</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>DEBERNARDIS, JOHN, F</creatorcontrib><creatorcontrib>ZINKOWSKI, RAYMOND, P</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DEBERNARDIS, JOHN, F</au><au>ZINKOWSKI, RAYMOND, P</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF DETECTING TAU PROTEIN AND TAU FRAGMENTS IN SERUM</title><date>2011-09-09</date><risdate>2011</risdate><abstract>The present invention provides quantitative methods for the detection of tau protein and/or tau fragments. More specifically, the present invention provides quantitative methods for diagnosing a tauopathy or ruling out a tauopathy as the cause of disease, particularly the diagnosis and ruling of Alzheimer's disease. The present invention further provides a method for diagnosing a tauopathy by computing the ratio of two detected tau proteins or tau fragments.
La présente invention concerne des procédés quantitatifs pour la détection de la protéine tau et/ou de fragments de tau. De façon plus spécifique, la présente invention porte sur des procédés quantitatifs pour le diagnostic d'une tauopathie ou pour écarter une tauopathie en tant que cause de maladie, en particulier, le diagnostic et l'élimination de la maladie d'Alzheimer. La présente invention porte en outre sur un procédé de diagnostic d'une tauopathie par le calcul du rapport de deux protéines tau ou fragments de tau détectés.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING |
| title | METHOD OF DETECTING TAU PROTEIN AND TAU FRAGMENTS IN SERUM |
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