SUSTAINED RELEASE TABLET FORMULATION CONTAINING ETODOLAC
This invention relates to a method for preparing a formulation in sustained release form that comprises 2 - (1,8- diethyl -4,9- dihydro - 3H -pyrano [3, 4 -b] indole - 1-il) acetic acid (Etodolac), which is an effective non-steroidal anti - inflammatory drug with a matrix agent, a buffer, a stabiliz...
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| creator | DENIZ, HILMI FIRAT, OMER FARUK YIGIT, ARIF PILLI, GULHAN |
| description | This invention relates to a method for preparing a formulation in sustained release form that comprises 2 - (1,8- diethyl -4,9- dihydro - 3H -pyrano [3, 4 -b] indole - 1-il) acetic acid (Etodolac), which is an effective non-steroidal anti - inflammatory drug with a matrix agent, a buffer, a stabilizing agent, a filter and a lubricant in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis symptoms and findings, in the treatment of acute gouty arthritis, acute muscular skeletal system pain, post - operative pain and dysmenorrhea by inhibiting the biosynthesis of prostaglandin.
La présente invention concerne un procédé de préparation d'une formulation à libération prolongée qui comprend de l'acide 2-(1,8-diéthyl-4,9-dihydro-3H-pyrano[3,4-b]indole-1-il)acétique (étodolac), qui est un médicament anti-inflammatoire non stéroïdien efficace comprenant un agent matriciel, un tampon, un agent stabilisant, un filtre et un lubrifiant dans le traitement des symptômes de l'arthrose, de la polyarthrite rhumatoïde et de la spondylarthrite ankylosante, dans le traitement de l'arthrite goutteuse aiguë, de la douleur aiguë du système musculo-squelettique, de la douleur postopératoire et de la dysménorrhée par inhibition de la biosynthèse de la prostaglandine. |
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La présente invention concerne un procédé de préparation d'une formulation à libération prolongée qui comprend de l'acide 2-(1,8-diéthyl-4,9-dihydro-3H-pyrano[3,4-b]indole-1-il)acétique (étodolac), qui est un médicament anti-inflammatoire non stéroïdien efficace comprenant un agent matriciel, un tampon, un agent stabilisant, un filtre et un lubrifiant dans le traitement des symptômes de l'arthrose, de la polyarthrite rhumatoïde et de la spondylarthrite ankylosante, dans le traitement de l'arthrite goutteuse aiguë, de la douleur aiguë du système musculo-squelettique, de la douleur postopératoire et de la dysménorrhée par inhibition de la biosynthèse de la prostaglandine.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110721&DB=EPODOC&CC=WO&NR=2011087464A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110721&DB=EPODOC&CC=WO&NR=2011087464A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DENIZ, HILMI</creatorcontrib><creatorcontrib>FIRAT, OMER FARUK</creatorcontrib><creatorcontrib>YIGIT, ARIF</creatorcontrib><creatorcontrib>PILLI, GULHAN</creatorcontrib><title>SUSTAINED RELEASE TABLET FORMULATION CONTAINING ETODOLAC</title><description>This invention relates to a method for preparing a formulation in sustained release form that comprises 2 - (1,8- diethyl -4,9- dihydro - 3H -pyrano [3, 4 -b] indole - 1-il) acetic acid (Etodolac), which is an effective non-steroidal anti - inflammatory drug with a matrix agent, a buffer, a stabilizing agent, a filter and a lubricant in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis symptoms and findings, in the treatment of acute gouty arthritis, acute muscular skeletal system pain, post - operative pain and dysmenorrhea by inhibiting the biosynthesis of prostaglandin.
La présente invention concerne un procédé de préparation d'une formulation à libération prolongée qui comprend de l'acide 2-(1,8-diéthyl-4,9-dihydro-3H-pyrano[3,4-b]indole-1-il)acétique (étodolac), qui est un médicament anti-inflammatoire non stéroïdien efficace comprenant un agent matriciel, un tampon, un agent stabilisant, un filtre et un lubrifiant dans le traitement des symptômes de l'arthrose, de la polyarthrite rhumatoïde et de la spondylarthrite ankylosante, dans le traitement de l'arthrite goutteuse aiguë, de la douleur aiguë du système musculo-squelettique, de la douleur postopératoire et de la dysménorrhée par inhibition de la biosynthèse de la prostaglandine.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAIDg0OcfT0c3VRCHL1cXUMdlUIcXTycQ1RcPMP8g31cQzx9PdTcPb3Ayny9HNXcA3xd_H3cXTmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBoaGBhbmJmYmjobGxKkCACQ5KaM</recordid><startdate>20110721</startdate><enddate>20110721</enddate><creator>DENIZ, HILMI</creator><creator>FIRAT, OMER FARUK</creator><creator>YIGIT, ARIF</creator><creator>PILLI, GULHAN</creator><scope>EVB</scope></search><sort><creationdate>20110721</creationdate><title>SUSTAINED RELEASE TABLET FORMULATION CONTAINING ETODOLAC</title><author>DENIZ, HILMI ; FIRAT, OMER FARUK ; YIGIT, ARIF ; PILLI, GULHAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2011087464A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2011</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>DENIZ, HILMI</creatorcontrib><creatorcontrib>FIRAT, OMER FARUK</creatorcontrib><creatorcontrib>YIGIT, ARIF</creatorcontrib><creatorcontrib>PILLI, GULHAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DENIZ, HILMI</au><au>FIRAT, OMER FARUK</au><au>YIGIT, ARIF</au><au>PILLI, GULHAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SUSTAINED RELEASE TABLET FORMULATION CONTAINING ETODOLAC</title><date>2011-07-21</date><risdate>2011</risdate><abstract>This invention relates to a method for preparing a formulation in sustained release form that comprises 2 - (1,8- diethyl -4,9- dihydro - 3H -pyrano [3, 4 -b] indole - 1-il) acetic acid (Etodolac), which is an effective non-steroidal anti - inflammatory drug with a matrix agent, a buffer, a stabilizing agent, a filter and a lubricant in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis symptoms and findings, in the treatment of acute gouty arthritis, acute muscular skeletal system pain, post - operative pain and dysmenorrhea by inhibiting the biosynthesis of prostaglandin.
La présente invention concerne un procédé de préparation d'une formulation à libération prolongée qui comprend de l'acide 2-(1,8-diéthyl-4,9-dihydro-3H-pyrano[3,4-b]indole-1-il)acétique (étodolac), qui est un médicament anti-inflammatoire non stéroïdien efficace comprenant un agent matriciel, un tampon, un agent stabilisant, un filtre et un lubrifiant dans le traitement des symptômes de l'arthrose, de la polyarthrite rhumatoïde et de la spondylarthrite ankylosante, dans le traitement de l'arthrite goutteuse aiguë, de la douleur aiguë du système musculo-squelettique, de la douleur postopératoire et de la dysménorrhée par inhibition de la biosynthèse de la prostaglandine.</abstract><oa>free_for_read</oa></addata></record> |
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| title | SUSTAINED RELEASE TABLET FORMULATION CONTAINING ETODOLAC |
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