PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS

The invention provides compounds that inhibit protein kinase CK2 activity (CK2 activity), and compositions containing such compounds. These compounds and compositions are useful for treating proliferative disorders such as cancer, as well as other kinase associated conditions including inflammation,...

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Hauptverfasser: HADDACH, MUSTAPHA, REGAN, COLLIN, F, RAVULA, SUCHITRA, RYCKMAN, DAVID, M, TRAN, JOE, A, RAFFAELE, NICHOLAS, B, PIERRE, FABRICE
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creator HADDACH, MUSTAPHA
REGAN, COLLIN, F
RAVULA, SUCHITRA
RYCKMAN, DAVID, M
TRAN, JOE, A
RAFFAELE, NICHOLAS, B
PIERRE, FABRICE
description The invention provides compounds that inhibit protein kinase CK2 activity (CK2 activity), and compositions containing such compounds. These compounds and compositions are useful for treating proliferative disorders such as cancer, as well as other kinase associated conditions including inflammation, pain, and certain immunological disorders, and have the following general formula (I).. La présente invention a pour objet des composés qui inhibent l'activité de protéine kinase CK2 (activité CK2), et des compositions contenant de tels composés. Ces composés et ces compositions sont utiles pour le traitement de troubles prolifératifs tels que le cancer, ainsi que d'autres états pathologiques associés à la kinase, y compris une inflammation, une douleur, et certains troubles immunologiques, et ont la formule générale suivante (I).
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS
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