VAL (8) GLP-1 COMPOSITION AND METHOD FOR TREATING FUNCTIONAL DYSPEPSIA AND/OR IRRITABLE BOWEL SYNDROME

A method of treating functional dyspepsia and/or irritable bowel syndrome in mammals in need of treatment is disclosed herein. The method comprises administering to the mammal a formulation by inhalation, wherein the formulation avoids first pass metabolism of the active ingredient. The method compr...

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Hauptverfasser: RICHARDSON, PETER, KENNY, ENDA, GRANT, MARSHALL, L, DANIELS, SCOTT, GREENE, STEPHANIE, HELLSTROM, PER, STOWELL, GRAYSON, W, SMITHSON, ANTHONY
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creator RICHARDSON, PETER
KENNY, ENDA
GRANT, MARSHALL, L
DANIELS, SCOTT
GREENE, STEPHANIE
HELLSTROM, PER
STOWELL, GRAYSON, W
SMITHSON, ANTHONY
description A method of treating functional dyspepsia and/or irritable bowel syndrome in mammals in need of treatment is disclosed herein. The method comprises administering to the mammal a formulation by inhalation, wherein the formulation avoids first pass metabolism of the active ingredient. The method comprises administering a formulation by pulmonary inhalation comprising a diketopiperazine and a glucagon-like peptide (GLP-1 ), analog, ROSE-010. La présente invention concerne un procédé de traitement de la dyspepsie fonctionnelle et/ou du syndrome du côlon irritable chez des mammifères ayant besoin d'un tel traitement. Ledit procédé comprend l'administration, à un mammifère, d'une formulation par inhalation, ladite formulation évitant le métabolisme de premier passage de l'ingrédient actif. Ce procédé comprend plus précisément l'administration d'une formulation par inhalation pulmonaire qui comporte un dicétopipérazine et un ROSE-010 analogue du peptide semblable au glucagon (GLP-1).
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title VAL (8) GLP-1 COMPOSITION AND METHOD FOR TREATING FUNCTIONAL DYSPEPSIA AND/OR IRRITABLE BOWEL SYNDROME
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