PROCESS FOR PREPARATION OF 5-SUBSTITUTED TETRAZOLES

The present invention is a process for preparing sterically hindered 5-substituted tetrazole, which comprises of reacting a nitrile with an organotin halide and an azide in presence of a phase transfer catalyst, in an organic solvent and a co- solvent at reflux temperature for 4 to 20 h. La présente...

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Hauptverfasser: POTLURI, RAMESH, BABU, DEHURY, SANJAY, KUMAR, VENKATA SUBHRAMANIAN, HARIHARA KRISHNAN
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creator POTLURI, RAMESH, BABU
DEHURY, SANJAY, KUMAR
VENKATA SUBHRAMANIAN, HARIHARA KRISHNAN
description The present invention is a process for preparing sterically hindered 5-substituted tetrazole, which comprises of reacting a nitrile with an organotin halide and an azide in presence of a phase transfer catalyst, in an organic solvent and a co- solvent at reflux temperature for 4 to 20 h. La présente invention concerne un procédé de préparation de tétrazole substitué en 5 stériquement encombré qui consiste à faire réagir un nitrile avec un halogénure d'organotine et un azide en présence d'un catalyseur de transfert de phase dans un solvant organique et un co-solvant à une température de reflux sur une durée de 4 à 24 h.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR PREPARATION OF 5-SUBSTITUTED TETRAZOLES
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