RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING
The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | TRIGG, WILLIAM JOHN WADSWORTH, HARRY JOHN |
| description | The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent of the present invention demonstrates good selective binding to the peripheral benzodiazepine receptor (PBR), in combination with good brain uptake and in vivo kinetics following administration to a subject.
La présente invention concerne un nouveau dérivé d'aryloxyalinine radiomarqué adapté pour l'imagerie in vivo. L'agent d'imagerie in vivo de la présente invention possède de meilleures propriétés pour l'imagerie in vivo que les agents d'imagerie in vivo connus à base de dérivés d'aryloxyalinine. L'agent d'imagerie in vivo de la présente invention présente une bonne liaison sélective au récepteur périphérique des benzodiazépines (PBR), combinée à une bonne absorption cérébrale et une bonne cinétique in vivo après l'administration à un sujet. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2010106166A3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2010106166A3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2010106166A33</originalsourceid><addsrcrecordid>eNrjZDAPcnTx9PdxdHL18XF1UQiIDPJ08fSL9FFwcQ3yDHMM8QxzDVZw8w9S8PTTDfMM81fw9HV09_Rz52FgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgaGQGhmaGbmaGxMnCoA8QspOQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING</title><source>esp@cenet</source><creator>TRIGG, WILLIAM JOHN ; WADSWORTH, HARRY JOHN</creator><creatorcontrib>TRIGG, WILLIAM JOHN ; WADSWORTH, HARRY JOHN</creatorcontrib><description>The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent of the present invention demonstrates good selective binding to the peripheral benzodiazepine receptor (PBR), in combination with good brain uptake and in vivo kinetics following administration to a subject.
La présente invention concerne un nouveau dérivé d'aryloxyalinine radiomarqué adapté pour l'imagerie in vivo. L'agent d'imagerie in vivo de la présente invention possède de meilleures propriétés pour l'imagerie in vivo que les agents d'imagerie in vivo connus à base de dérivés d'aryloxyalinine. L'agent d'imagerie in vivo de la présente invention présente une bonne liaison sélective au récepteur périphérique des benzodiazépines (PBR), combinée à une bonne absorption cérébrale et une bonne cinétique in vivo après l'administration à un sujet.</description><language>eng ; fre</language><subject>APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110331&DB=EPODOC&CC=WO&NR=2010106166A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110331&DB=EPODOC&CC=WO&NR=2010106166A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TRIGG, WILLIAM JOHN</creatorcontrib><creatorcontrib>WADSWORTH, HARRY JOHN</creatorcontrib><title>RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING</title><description>The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent of the present invention demonstrates good selective binding to the peripheral benzodiazepine receptor (PBR), in combination with good brain uptake and in vivo kinetics following administration to a subject.
La présente invention concerne un nouveau dérivé d'aryloxyalinine radiomarqué adapté pour l'imagerie in vivo. L'agent d'imagerie in vivo de la présente invention possède de meilleures propriétés pour l'imagerie in vivo que les agents d'imagerie in vivo connus à base de dérivés d'aryloxyalinine. L'agent d'imagerie in vivo de la présente invention présente une bonne liaison sélective au récepteur périphérique des benzodiazépines (PBR), combinée à une bonne absorption cérébrale et une bonne cinétique in vivo après l'administration à un sujet.</description><subject>APPARATUS THEREFOR</subject><subject>CHEMISTRY</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAPcnTx9PdxdHL18XF1UQiIDPJ08fSL9FFwcQ3yDHMM8QxzDVZw8w9S8PTTDfMM81fw9HV09_Rz52FgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgaGQGhmaGbmaGxMnCoA8QspOQ</recordid><startdate>20110331</startdate><enddate>20110331</enddate><creator>TRIGG, WILLIAM JOHN</creator><creator>WADSWORTH, HARRY JOHN</creator><scope>EVB</scope></search><sort><creationdate>20110331</creationdate><title>RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING</title><author>TRIGG, WILLIAM JOHN ; WADSWORTH, HARRY JOHN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2010106166A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2011</creationdate><topic>APPARATUS THEREFOR</topic><topic>CHEMISTRY</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>TRIGG, WILLIAM JOHN</creatorcontrib><creatorcontrib>WADSWORTH, HARRY JOHN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TRIGG, WILLIAM JOHN</au><au>WADSWORTH, HARRY JOHN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING</title><date>2011-03-31</date><risdate>2011</risdate><abstract>The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent of the present invention demonstrates good selective binding to the peripheral benzodiazepine receptor (PBR), in combination with good brain uptake and in vivo kinetics following administration to a subject.
La présente invention concerne un nouveau dérivé d'aryloxyalinine radiomarqué adapté pour l'imagerie in vivo. L'agent d'imagerie in vivo de la présente invention possède de meilleures propriétés pour l'imagerie in vivo que les agents d'imagerie in vivo connus à base de dérivés d'aryloxyalinine. L'agent d'imagerie in vivo de la présente invention présente une bonne liaison sélective au récepteur périphérique des benzodiazépines (PBR), combinée à une bonne absorption cérébrale et une bonne cinétique in vivo après l'administration à un sujet.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2010106166A3 |
| source | esp@cenet |
| subjects | APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T18%3A10%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=TRIGG,%20WILLIAM%20JOHN&rft.date=2011-03-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2010106166A3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |