NANOPARTICLE PHARMACEUTICAL FORMULATIONS

The present invention is directed to methods of preparing nanoparticles of aqueous-insoluble compounds, particularly aqueous-insoluble bioactive (drug) compounds, and to compositions and medicaments obtained by these methods. These methods, compositions, and other inventive aspects of the present in...

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Hauptverfasser: THASSU, DEEPAK, HOLT, KRIS, VIOLANTE, MICHAEL, R
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creator THASSU, DEEPAK
HOLT, KRIS
VIOLANTE, MICHAEL, R
description The present invention is directed to methods of preparing nanoparticles of aqueous-insoluble compounds, particularly aqueous-insoluble bioactive (drug) compounds, and to compositions and medicaments obtained by these methods. These methods, compositions, and other inventive aspects of the present invention are based particularly on the use of bile acid compound(s) to prepare nanoparticles of aqueous-insoluble compounds. La présente invention concerne des méthodes de préparation de nanoparticules de composés insolubles dans des solvants aqueux, particulièrement des composés bioactifs (médicaments) insolubles dans des solvants aqueux, et des compositions et des médicaments obtenus par ces méthodes. Ces méthodes, compositions, et autres aspects de la présente invention sont basés particulièrement sur l'utilisation de composé(s) d'acide biliaire pour préparer des nanoparticles de composés insolubles dans des solvants aqueux.
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subjects DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SURGERY
title NANOPARTICLE PHARMACEUTICAL FORMULATIONS
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