3-AMINOPYRROLIDINE DERIVATIVES AS CCR2 ANTAGONISTS
The present invention relates to compounds of chemical formula 1 and having CCR2 (chemokine receptor 2) antagonistic effects, and salts or isomers thereof. These compounds are very useful for treating, preventing, or relieving rheumatoid arthritis, arteriosclerosis, multiple sclerosis, asthma, and v...
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| creator | OH, YOUNA CHOI, WOON-SUN RHEE, CHUNG KEUN LEE, JUNG-OK OAK, MIN-HO LIM, JEE WOONG KIM, JONG-HOON NA, YONGHO SOHN, JUNG-DUK |
| description | The present invention relates to compounds of chemical formula 1 and having CCR2 (chemokine receptor 2) antagonistic effects, and salts or isomers thereof. These compounds are very useful for treating, preventing, or relieving rheumatoid arthritis, arteriosclerosis, multiple sclerosis, asthma, and various diseases related to CCR2.
La présente invention porte sur des composés de la formule chimique 1 possédant des effets antagonistes de CCR2 (récepteur de chimiokine 2), ainsi que sur des sels ou des isomères correspondants. Lesdits composés se révèlent extrêmement utiles pour traiter, prévenir ou soulager l'arthrite rhumatoïde, l'artériosclérose, la sclérose en plaques, l'asthme et diverses maladies liées à CCR2. |
| format | Patent |
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La présente invention porte sur des composés de la formule chimique 1 possédant des effets antagonistes de CCR2 (récepteur de chimiokine 2), ainsi que sur des sels ou des isomères correspondants. Lesdits composés se révèlent extrêmement utiles pour traiter, prévenir ou soulager l'arthrite rhumatoïde, l'artériosclérose, la sclérose en plaques, l'asthme et diverses maladies liées à CCR2.</description><language>eng ; fre ; kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100701&DB=EPODOC&CC=WO&NR=2010074409A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100701&DB=EPODOC&CC=WO&NR=2010074409A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OH, YOUNA</creatorcontrib><creatorcontrib>CHOI, WOON-SUN</creatorcontrib><creatorcontrib>RHEE, CHUNG KEUN</creatorcontrib><creatorcontrib>LEE, JUNG-OK</creatorcontrib><creatorcontrib>OAK, MIN-HO</creatorcontrib><creatorcontrib>LIM, JEE WOONG</creatorcontrib><creatorcontrib>KIM, JONG-HOON</creatorcontrib><creatorcontrib>NA, YONGHO</creatorcontrib><creatorcontrib>SOHN, JUNG-DUK</creatorcontrib><title>3-AMINOPYRROLIDINE DERIVATIVES AS CCR2 ANTAGONISTS</title><description>The present invention relates to compounds of chemical formula 1 and having CCR2 (chemokine receptor 2) antagonistic effects, and salts or isomers thereof. These compounds are very useful for treating, preventing, or relieving rheumatoid arthritis, arteriosclerosis, multiple sclerosis, asthma, and various diseases related to CCR2.
La présente invention porte sur des composés de la formule chimique 1 possédant des effets antagonistes de CCR2 (récepteur de chimiokine 2), ainsi que sur des sels ou des isomères correspondants. Lesdits composés se révèlent extrêmement utiles pour traiter, prévenir ou soulager l'arthrite rhumatoïde, l'artériosclérose, la sclérose en plaques, l'asthme et diverses maladies liées à CCR2.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAy1nX09fTzD4gMCvL38XTx9HNVcHEN8gxzDPEMcw1WcAxWcHYOMlJw9AtxdPf38wwOCeZhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGhgYG5iYmBpaORsbEqQIAIHYn1Q</recordid><startdate>20100701</startdate><enddate>20100701</enddate><creator>OH, YOUNA</creator><creator>CHOI, WOON-SUN</creator><creator>RHEE, CHUNG KEUN</creator><creator>LEE, JUNG-OK</creator><creator>OAK, MIN-HO</creator><creator>LIM, JEE WOONG</creator><creator>KIM, JONG-HOON</creator><creator>NA, YONGHO</creator><creator>SOHN, JUNG-DUK</creator><scope>EVB</scope></search><sort><creationdate>20100701</creationdate><title>3-AMINOPYRROLIDINE DERIVATIVES AS CCR2 ANTAGONISTS</title><author>OH, YOUNA ; CHOI, WOON-SUN ; RHEE, CHUNG KEUN ; LEE, JUNG-OK ; OAK, MIN-HO ; LIM, JEE WOONG ; KIM, JONG-HOON ; NA, YONGHO ; SOHN, JUNG-DUK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2010074409A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; kor</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>OH, YOUNA</creatorcontrib><creatorcontrib>CHOI, WOON-SUN</creatorcontrib><creatorcontrib>RHEE, CHUNG KEUN</creatorcontrib><creatorcontrib>LEE, JUNG-OK</creatorcontrib><creatorcontrib>OAK, MIN-HO</creatorcontrib><creatorcontrib>LIM, JEE WOONG</creatorcontrib><creatorcontrib>KIM, JONG-HOON</creatorcontrib><creatorcontrib>NA, YONGHO</creatorcontrib><creatorcontrib>SOHN, JUNG-DUK</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OH, YOUNA</au><au>CHOI, WOON-SUN</au><au>RHEE, CHUNG KEUN</au><au>LEE, JUNG-OK</au><au>OAK, MIN-HO</au><au>LIM, JEE WOONG</au><au>KIM, JONG-HOON</au><au>NA, YONGHO</au><au>SOHN, JUNG-DUK</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>3-AMINOPYRROLIDINE DERIVATIVES AS CCR2 ANTAGONISTS</title><date>2010-07-01</date><risdate>2010</risdate><abstract>The present invention relates to compounds of chemical formula 1 and having CCR2 (chemokine receptor 2) antagonistic effects, and salts or isomers thereof. These compounds are very useful for treating, preventing, or relieving rheumatoid arthritis, arteriosclerosis, multiple sclerosis, asthma, and various diseases related to CCR2.
La présente invention porte sur des composés de la formule chimique 1 possédant des effets antagonistes de CCR2 (récepteur de chimiokine 2), ainsi que sur des sels ou des isomères correspondants. Lesdits composés se révèlent extrêmement utiles pour traiter, prévenir ou soulager l'arthrite rhumatoïde, l'artériosclérose, la sclérose en plaques, l'asthme et diverses maladies liées à CCR2.</abstract><oa>free_for_read</oa></addata></record> |
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| title | 3-AMINOPYRROLIDINE DERIVATIVES AS CCR2 ANTAGONISTS |
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