PROLYL HYDROXYLASE INHIBITORS

The invention described herein relates to certain 2,4-dioxo-1,2,3,4-tetrahydrothieno[3,2- d]pyrimidme-6-carboxamide derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GHERGUROVICH, JONATHAN M, WANG, YOUNGHUI, SCHULZ, MARK, JAMES
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention described herein relates to certain 2,4-dioxo-1,2,3,4-tetrahydrothieno[3,2- d]pyrimidme-6-carboxamide derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example. L'invention porte sur certains dérivés de la 2,4-dioxo-1,2,3,4-tétrahydrothiéno[3,2-d]pyrimidine-6-carboxamide de formule (I), qui sont des antagonistes de prolyl hydroxylases HIF et qui sont utiles pour traiter des maladies bénéficiant de l'inhibition de cette enzyme, l'anémie en étant une exemple.