PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS

Pharmaceutical compositions comprising bortezomib for oral or parenteral administration. Specific aspects relate to stable, sugar free pharmaceutical compositions of bortezomib, including its pharmaceutically acceptable salts or solvates, in the form of ready-to-use solutions, lyophilized forms, or...

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Hauptverfasser: CHANDRKANTH, KENI DEVENDRA, SRIDHAR, MITTAPALLY, KOCHERLAKOTA, CHANDRASEKHAR, NALLAMOTHU, LAVANYA, PILLAI, RAVIRAJ SUKUMAR, SREEDHAR, BANDARI, KRANTHIKUMAR, HINGE, SHANTREDDY, SOOGAREDDY CHANNAREDDY, KOVORU, KRISHNAM RAJU, BANDA, NAGARAJU, CHHAGAN, WAGH SANJAY
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Pharmaceutical compositions comprising bortezomib for oral or parenteral administration. Specific aspects relate to stable, sugar free pharmaceutical compositions of bortezomib, including its pharmaceutically acceptable salts or solvates, in the form of ready-to-use solutions, lyophilized forms, or physical admixtures, and the preparation thereof. Other aspects include processes for preparing compositions and methods of using compositions for treating various types of cancers in mammals. L'invention concerne des compositions pharmaceutiques qui comprennent du bortezomib pour une administration orale ou parentérale. Des aspects particuliers concernent des compositions pharmaceutiques stables sans sucre de bortezomib, y compris ses sels ou solvates pharmaceutiquement acceptables, sous la forme de solutions prêtes à l'emploi, des formes lyophilisées ou des mélanges physiques, et leur préparation. D'autres aspects comprennent des procédés de préparation des compositions et des méthodes d'utilisation des compositions pour traiter divers types de cancers chez des mammifères.