PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS

A process for preparing isoxazole compounds of formula (I) in which a nitroaryl of the formula (II) is contacted with an alkyl acetoacetate of the formula (III) or a salt thereof in the presence of an activating agent and a base to provide the isoxazole compound. L'invention concerne un procédé...

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Hauptverfasser: GREEN, GEORGE, DAVID, GODSCHALX, JAMES, P
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GODSCHALX, JAMES, P
description A process for preparing isoxazole compounds of formula (I) in which a nitroaryl of the formula (II) is contacted with an alkyl acetoacetate of the formula (III) or a salt thereof in the presence of an activating agent and a base to provide the isoxazole compound. L'invention concerne un procédé de préparation de composés d'isoxazole de la formule (I) dans lequel un nitroaryle de la formule (II) est mis en contact avec un acétoacétate d'alkyle de la formule (III) ou un sel de celui-ci en présence d'un agent d'activation et d'une base pour produire le composé d'isoxazole.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS
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