TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS
Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases. La présente invention co...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | RAST, BRYSON DELISLE, ROBERT KIRK MARMSATER, FREDRIK, P DAVIS, T. GREGG TOPALOV, GEORGE T JACKSON, LEILA, J WRIGHT, A. DALE CELESTE, LAURA L LYSSIKATOS, JOSEPH, P MUNSON, MARK, C ZHAO, QIAN KALLAN, NICHOLAS C PHENEGER, JED HICKEN, ERIK, JAMES GROSS, STEFAN, D ROBINSON, JOHN, E GRESCHUK, JULIE MARIE ALLEN, SHELLEY SCHLACHTER, STEPHEN T |
| description | Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.
La présente invention concerne les composés de formule (I), dans laquelle A, B, R1, R1a, R2, R3, R4, R5, R6, et R7 ont les significations données dans la spécification, qui sont des inhibiteurs de la tyrosine du récepteur utiles dans le traitement de maladies et troubles associés aux cellules immunitaires, tels que les maladies inflammatoires et auto-immunes. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2010022076A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2010022076A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2010022076A13</originalsourceid><addsrcrecordid>eNrjZDAOCfJ0jPL38Q-IDPJ08fRzVXD29w3wD_VzCVZwDFYI8PRV8Pb0cwx2VfD08_B08gzxDwrmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBoYGBkZGBuZmjobGxKkCAG1SKFI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS</title><source>esp@cenet</source><creator>RAST, BRYSON ; DELISLE, ROBERT KIRK ; MARMSATER, FREDRIK, P ; DAVIS, T. GREGG ; TOPALOV, GEORGE T ; JACKSON, LEILA, J ; WRIGHT, A. DALE ; CELESTE, LAURA L ; LYSSIKATOS, JOSEPH, P ; MUNSON, MARK, C ; ZHAO, QIAN ; KALLAN, NICHOLAS C ; PHENEGER, JED ; HICKEN, ERIK, JAMES ; GROSS, STEFAN, D ; ROBINSON, JOHN, E ; GRESCHUK, JULIE MARIE ; ALLEN, SHELLEY ; SCHLACHTER, STEPHEN T</creator><creatorcontrib>RAST, BRYSON ; DELISLE, ROBERT KIRK ; MARMSATER, FREDRIK, P ; DAVIS, T. GREGG ; TOPALOV, GEORGE T ; JACKSON, LEILA, J ; WRIGHT, A. DALE ; CELESTE, LAURA L ; LYSSIKATOS, JOSEPH, P ; MUNSON, MARK, C ; ZHAO, QIAN ; KALLAN, NICHOLAS C ; PHENEGER, JED ; HICKEN, ERIK, JAMES ; GROSS, STEFAN, D ; ROBINSON, JOHN, E ; GRESCHUK, JULIE MARIE ; ALLEN, SHELLEY ; SCHLACHTER, STEPHEN T</creatorcontrib><description>Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.
La présente invention concerne les composés de formule (I), dans laquelle A, B, R1, R1a, R2, R3, R4, R5, R6, et R7 ont les significations données dans la spécification, qui sont des inhibiteurs de la tyrosine du récepteur utiles dans le traitement de maladies et troubles associés aux cellules immunitaires, tels que les maladies inflammatoires et auto-immunes.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100225&DB=EPODOC&CC=WO&NR=2010022076A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100225&DB=EPODOC&CC=WO&NR=2010022076A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RAST, BRYSON</creatorcontrib><creatorcontrib>DELISLE, ROBERT KIRK</creatorcontrib><creatorcontrib>MARMSATER, FREDRIK, P</creatorcontrib><creatorcontrib>DAVIS, T. GREGG</creatorcontrib><creatorcontrib>TOPALOV, GEORGE T</creatorcontrib><creatorcontrib>JACKSON, LEILA, J</creatorcontrib><creatorcontrib>WRIGHT, A. DALE</creatorcontrib><creatorcontrib>CELESTE, LAURA L</creatorcontrib><creatorcontrib>LYSSIKATOS, JOSEPH, P</creatorcontrib><creatorcontrib>MUNSON, MARK, C</creatorcontrib><creatorcontrib>ZHAO, QIAN</creatorcontrib><creatorcontrib>KALLAN, NICHOLAS C</creatorcontrib><creatorcontrib>PHENEGER, JED</creatorcontrib><creatorcontrib>HICKEN, ERIK, JAMES</creatorcontrib><creatorcontrib>GROSS, STEFAN, D</creatorcontrib><creatorcontrib>ROBINSON, JOHN, E</creatorcontrib><creatorcontrib>GRESCHUK, JULIE MARIE</creatorcontrib><creatorcontrib>ALLEN, SHELLEY</creatorcontrib><creatorcontrib>SCHLACHTER, STEPHEN T</creatorcontrib><title>TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS</title><description>Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.
La présente invention concerne les composés de formule (I), dans laquelle A, B, R1, R1a, R2, R3, R4, R5, R6, et R7 ont les significations données dans la spécification, qui sont des inhibiteurs de la tyrosine du récepteur utiles dans le traitement de maladies et troubles associés aux cellules immunitaires, tels que les maladies inflammatoires et auto-immunes.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAOCfJ0jPL38Q-IDPJ08fRzVXD29w3wD_VzCVZwDFYI8PRV8Pb0cwx2VfD08_B08gzxDwrmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBoYGBkZGBuZmjobGxKkCAG1SKFI</recordid><startdate>20100225</startdate><enddate>20100225</enddate><creator>RAST, BRYSON</creator><creator>DELISLE, ROBERT KIRK</creator><creator>MARMSATER, FREDRIK, P</creator><creator>DAVIS, T. GREGG</creator><creator>TOPALOV, GEORGE T</creator><creator>JACKSON, LEILA, J</creator><creator>WRIGHT, A. DALE</creator><creator>CELESTE, LAURA L</creator><creator>LYSSIKATOS, JOSEPH, P</creator><creator>MUNSON, MARK, C</creator><creator>ZHAO, QIAN</creator><creator>KALLAN, NICHOLAS C</creator><creator>PHENEGER, JED</creator><creator>HICKEN, ERIK, JAMES</creator><creator>GROSS, STEFAN, D</creator><creator>ROBINSON, JOHN, E</creator><creator>GRESCHUK, JULIE MARIE</creator><creator>ALLEN, SHELLEY</creator><creator>SCHLACHTER, STEPHEN T</creator><scope>EVB</scope></search><sort><creationdate>20100225</creationdate><title>TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS</title><author>RAST, BRYSON ; DELISLE, ROBERT KIRK ; MARMSATER, FREDRIK, P ; DAVIS, T. GREGG ; TOPALOV, GEORGE T ; JACKSON, LEILA, J ; WRIGHT, A. DALE ; CELESTE, LAURA L ; LYSSIKATOS, JOSEPH, P ; MUNSON, MARK, C ; ZHAO, QIAN ; KALLAN, NICHOLAS C ; PHENEGER, JED ; HICKEN, ERIK, JAMES ; GROSS, STEFAN, D ; ROBINSON, JOHN, E ; GRESCHUK, JULIE MARIE ; ALLEN, SHELLEY ; SCHLACHTER, STEPHEN T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2010022076A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>RAST, BRYSON</creatorcontrib><creatorcontrib>DELISLE, ROBERT KIRK</creatorcontrib><creatorcontrib>MARMSATER, FREDRIK, P</creatorcontrib><creatorcontrib>DAVIS, T. GREGG</creatorcontrib><creatorcontrib>TOPALOV, GEORGE T</creatorcontrib><creatorcontrib>JACKSON, LEILA, J</creatorcontrib><creatorcontrib>WRIGHT, A. DALE</creatorcontrib><creatorcontrib>CELESTE, LAURA L</creatorcontrib><creatorcontrib>LYSSIKATOS, JOSEPH, P</creatorcontrib><creatorcontrib>MUNSON, MARK, C</creatorcontrib><creatorcontrib>ZHAO, QIAN</creatorcontrib><creatorcontrib>KALLAN, NICHOLAS C</creatorcontrib><creatorcontrib>PHENEGER, JED</creatorcontrib><creatorcontrib>HICKEN, ERIK, JAMES</creatorcontrib><creatorcontrib>GROSS, STEFAN, D</creatorcontrib><creatorcontrib>ROBINSON, JOHN, E</creatorcontrib><creatorcontrib>GRESCHUK, JULIE MARIE</creatorcontrib><creatorcontrib>ALLEN, SHELLEY</creatorcontrib><creatorcontrib>SCHLACHTER, STEPHEN T</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RAST, BRYSON</au><au>DELISLE, ROBERT KIRK</au><au>MARMSATER, FREDRIK, P</au><au>DAVIS, T. GREGG</au><au>TOPALOV, GEORGE T</au><au>JACKSON, LEILA, J</au><au>WRIGHT, A. DALE</au><au>CELESTE, LAURA L</au><au>LYSSIKATOS, JOSEPH, P</au><au>MUNSON, MARK, C</au><au>ZHAO, QIAN</au><au>KALLAN, NICHOLAS C</au><au>PHENEGER, JED</au><au>HICKEN, ERIK, JAMES</au><au>GROSS, STEFAN, D</au><au>ROBINSON, JOHN, E</au><au>GRESCHUK, JULIE MARIE</au><au>ALLEN, SHELLEY</au><au>SCHLACHTER, STEPHEN T</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS</title><date>2010-02-25</date><risdate>2010</risdate><abstract>Compounds of Formula (I), in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of immune cell-associated diseases and disorders, such as inflammatory and autoimmune diseases.
La présente invention concerne les composés de formule (I), dans laquelle A, B, R1, R1a, R2, R3, R4, R5, R6, et R7 ont les significations données dans la spécification, qui sont des inhibiteurs de la tyrosine du récepteur utiles dans le traitement de maladies et troubles associés aux cellules immunitaires, tels que les maladies inflammatoires et auto-immunes.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2010022076A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T02%3A52%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=RAST,%20BRYSON&rft.date=2010-02-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2010022076A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |