PROCESS FOR SELECTIVELY PRODUCING A PYRIDOBENZOXAZINE CARBOXYLIC ACID HEMIHYDRATE
A novel and practical process for selectively producing a pyridobenzoxazine carboxylic acid hemihydrate (e.g., (S)-9-fluoro-3-methyl-10-(4-methyl-l-piperazinyl)-7-oxo- 2, 3-dihydro-7H-pyrido- [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acid hemihydrate) in high yield via crystallization from an org...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | WANG, ZHEQING GUO, WEIFENG SHU, LIJIAN JIN, CHENMING SHEN, XIAOFENG ZHU, HANG, CHANG YANG, PINGAI |
| description | A novel and practical process for selectively producing a pyridobenzoxazine carboxylic acid hemihydrate (e.g., (S)-9-fluoro-3-methyl-10-(4-methyl-l-piperazinyl)-7-oxo- 2, 3-dihydro-7H-pyrido- [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acid hemihydrate) in high yield via crystallization from an organic solvent or a mixed organic solvent system containing a calculated amount of water released from sodium sulfate decahydrate under gradually heating.
L'invention porte sur un procédé nouveau et pratique pour fabriquer de façon sélective un acide pyridobenzoxazine carboxylique hémihydraté (par exemple, l'acide (S)-9-fluoro-3-méthyl-10-(4-méthyl-1-pipérazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3-de][1,4]benzoxazine-6-carboxylique hémihydraté) avec un haut rendement par cristallisation à partir d'un solvant organique ou d'un système de solvant organique mixte contenant une quantité calculée d'eau libérée par le sulfate de sodium décahydraté sous chauffage progressif. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2010016851A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2010016851A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2010016851A13</originalsourceid><addsrcrecordid>eNrjZAgMCPJ3dg0OVnDzD1IIdvVxdQ7xDHP1iVQAiruEOnv6uSs4KgREBnm6-Du5-kX5RzhGefq5Kjg7Bjn5R0T6eDorODp7uih4uPp6ekS6BDmGuPIwsKYl5hSn8kJpbgZlN9cQZw_d1IL8-NTigsTk1LzUkvhwfyMDQwMDQzMLU0NHQ2PiVAEAomkwrA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR SELECTIVELY PRODUCING A PYRIDOBENZOXAZINE CARBOXYLIC ACID HEMIHYDRATE</title><source>esp@cenet</source><creator>WANG, ZHEQING ; GUO, WEIFENG ; SHU, LIJIAN ; JIN, CHENMING ; SHEN, XIAOFENG ; ZHU, HANG, CHANG ; YANG, PINGAI</creator><creatorcontrib>WANG, ZHEQING ; GUO, WEIFENG ; SHU, LIJIAN ; JIN, CHENMING ; SHEN, XIAOFENG ; ZHU, HANG, CHANG ; YANG, PINGAI</creatorcontrib><description>A novel and practical process for selectively producing a pyridobenzoxazine carboxylic acid hemihydrate (e.g., (S)-9-fluoro-3-methyl-10-(4-methyl-l-piperazinyl)-7-oxo- 2, 3-dihydro-7H-pyrido- [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acid hemihydrate) in high yield via crystallization from an organic solvent or a mixed organic solvent system containing a calculated amount of water released from sodium sulfate decahydrate under gradually heating.
L'invention porte sur un procédé nouveau et pratique pour fabriquer de façon sélective un acide pyridobenzoxazine carboxylique hémihydraté (par exemple, l'acide (S)-9-fluoro-3-méthyl-10-(4-méthyl-1-pipérazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3-de][1,4]benzoxazine-6-carboxylique hémihydraté) avec un haut rendement par cristallisation à partir d'un solvant organique ou d'un système de solvant organique mixte contenant une quantité calculée d'eau libérée par le sulfate de sodium décahydraté sous chauffage progressif.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100211&DB=EPODOC&CC=WO&NR=2010016851A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100211&DB=EPODOC&CC=WO&NR=2010016851A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WANG, ZHEQING</creatorcontrib><creatorcontrib>GUO, WEIFENG</creatorcontrib><creatorcontrib>SHU, LIJIAN</creatorcontrib><creatorcontrib>JIN, CHENMING</creatorcontrib><creatorcontrib>SHEN, XIAOFENG</creatorcontrib><creatorcontrib>ZHU, HANG, CHANG</creatorcontrib><creatorcontrib>YANG, PINGAI</creatorcontrib><title>PROCESS FOR SELECTIVELY PRODUCING A PYRIDOBENZOXAZINE CARBOXYLIC ACID HEMIHYDRATE</title><description>A novel and practical process for selectively producing a pyridobenzoxazine carboxylic acid hemihydrate (e.g., (S)-9-fluoro-3-methyl-10-(4-methyl-l-piperazinyl)-7-oxo- 2, 3-dihydro-7H-pyrido- [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acid hemihydrate) in high yield via crystallization from an organic solvent or a mixed organic solvent system containing a calculated amount of water released from sodium sulfate decahydrate under gradually heating.
L'invention porte sur un procédé nouveau et pratique pour fabriquer de façon sélective un acide pyridobenzoxazine carboxylique hémihydraté (par exemple, l'acide (S)-9-fluoro-3-méthyl-10-(4-méthyl-1-pipérazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3-de][1,4]benzoxazine-6-carboxylique hémihydraté) avec un haut rendement par cristallisation à partir d'un solvant organique ou d'un système de solvant organique mixte contenant une quantité calculée d'eau libérée par le sulfate de sodium décahydraté sous chauffage progressif.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgMCPJ3dg0OVnDzD1IIdvVxdQ7xDHP1iVQAiruEOnv6uSs4KgREBnm6-Du5-kX5RzhGefq5Kjg7Bjn5R0T6eDorODp7uih4uPp6ekS6BDmGuPIwsKYl5hSn8kJpbgZlN9cQZw_d1IL8-NTigsTk1LzUkvhwfyMDQwMDQzMLU0NHQ2PiVAEAomkwrA</recordid><startdate>20100211</startdate><enddate>20100211</enddate><creator>WANG, ZHEQING</creator><creator>GUO, WEIFENG</creator><creator>SHU, LIJIAN</creator><creator>JIN, CHENMING</creator><creator>SHEN, XIAOFENG</creator><creator>ZHU, HANG, CHANG</creator><creator>YANG, PINGAI</creator><scope>EVB</scope></search><sort><creationdate>20100211</creationdate><title>PROCESS FOR SELECTIVELY PRODUCING A PYRIDOBENZOXAZINE CARBOXYLIC ACID HEMIHYDRATE</title><author>WANG, ZHEQING ; GUO, WEIFENG ; SHU, LIJIAN ; JIN, CHENMING ; SHEN, XIAOFENG ; ZHU, HANG, CHANG ; YANG, PINGAI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2010016851A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG, ZHEQING</creatorcontrib><creatorcontrib>GUO, WEIFENG</creatorcontrib><creatorcontrib>SHU, LIJIAN</creatorcontrib><creatorcontrib>JIN, CHENMING</creatorcontrib><creatorcontrib>SHEN, XIAOFENG</creatorcontrib><creatorcontrib>ZHU, HANG, CHANG</creatorcontrib><creatorcontrib>YANG, PINGAI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG, ZHEQING</au><au>GUO, WEIFENG</au><au>SHU, LIJIAN</au><au>JIN, CHENMING</au><au>SHEN, XIAOFENG</au><au>ZHU, HANG, CHANG</au><au>YANG, PINGAI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR SELECTIVELY PRODUCING A PYRIDOBENZOXAZINE CARBOXYLIC ACID HEMIHYDRATE</title><date>2010-02-11</date><risdate>2010</risdate><abstract>A novel and practical process for selectively producing a pyridobenzoxazine carboxylic acid hemihydrate (e.g., (S)-9-fluoro-3-methyl-10-(4-methyl-l-piperazinyl)-7-oxo- 2, 3-dihydro-7H-pyrido- [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acid hemihydrate) in high yield via crystallization from an organic solvent or a mixed organic solvent system containing a calculated amount of water released from sodium sulfate decahydrate under gradually heating.
L'invention porte sur un procédé nouveau et pratique pour fabriquer de façon sélective un acide pyridobenzoxazine carboxylique hémihydraté (par exemple, l'acide (S)-9-fluoro-3-méthyl-10-(4-méthyl-1-pipérazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3-de][1,4]benzoxazine-6-carboxylique hémihydraté) avec un haut rendement par cristallisation à partir d'un solvant organique ou d'un système de solvant organique mixte contenant une quantité calculée d'eau libérée par le sulfate de sodium décahydraté sous chauffage progressif.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2010016851A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | PROCESS FOR SELECTIVELY PRODUCING A PYRIDOBENZOXAZINE CARBOXYLIC ACID HEMIHYDRATE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T15%3A35%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=WANG,%20ZHEQING&rft.date=2010-02-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2010016851A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |