PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES

The present invention relates to methods of making compounds that inhibit 11-ß-hydroxysteroid dehydrogenase type 1 enzyme (11-ß HSD1). One method comprises (a) contacting a compound of formula (II) with a chiral base, deprotonating agent, and an alkylating agent R3-LG, (b) contacting the product of...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	HANSEN, KARL B, KLINGENSMITH, LIANE, MARTINELLI, MICHAEL, LARROW, JAY, MONIZ, GEORGE A, FRIZZLE, MATTHEW J, FAUL, MARGARET, BERNARD, CHARLES
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!