TRIGGERED RELEASE OF DRUGS FROM POLYMER PARTICLES

The present invention includes compositions and methods for the controlled delivery of active agents, e.g., drugs, based on one or more release triggers found in the environment in which the active agent-loaded particle is located. The composition and methods include a polymer network having a polym...

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Hauptverfasser: WANAKULE, PRINDA, ROY, KRISHNENDU, SINGH, ANKUR
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creator WANAKULE, PRINDA
ROY, KRISHNENDU
SINGH, ANKUR
description The present invention includes compositions and methods for the controlled delivery of active agents, e.g., drugs, based on one or more release triggers found in the environment in which the active agent-loaded particle is located. The composition and methods include a polymer network having a polymer cross-linked by peptides that include one or more proteolytic cleavage sites. La présente invention porte sur des compositions et des procédés pour l'administration contrôlée d'agents actifs, par exemple de médicaments, à base d'un ou plusieurs déclencheurs de libération trouvés dans l'environnement dans lequel les particules chargées d'agent actif sont situées. La composition et les procédés comprennent un réseau polymère ayant un polymère réticulé par des peptides qui comprennent un ou plusieurs sites de clivage protéolytiques.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TRIGGERED RELEASE OF DRUGS FROM POLYMER PARTICLES
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