TOPICAL FORMULATION COMPRISING ADAPALENE MICROSPHERES AND CLINDAMYCIN
The present invention relates to stable fixed dose topical formulations comprising an antiacne agent and an antibiotic, which exhibit storage stability at a temperature of about 40 °C and relative humidity of about 75 % for a period of at least 3 months. Particularly, the present invention relates t...
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| creator | BHAMRE, NITIN BABULAL CHAUDHARI, SUNIL SUDHAKAR TRIVEDI, GIRISH RAMAKRISHNA SHARMA, AKHILESH DAYANAND DHUPPAD, ULHAS RAMESHCHANDRA DONGRE, PRASHANT |
| description | The present invention relates to stable fixed dose topical formulations comprising an antiacne agent and an antibiotic, which exhibit storage stability at a temperature of about 40 °C and relative humidity of about 75 % for a period of at least 3 months. Particularly, the present invention relates to stable fixed dose topical formulations comprising therapeutically effective amounts of (a) adapalene-containing microspheres and (b) clindamycin, a process for their preparation thereof and their use for the treatment of acne.
Cette invention concerne des formulations topiques stables sous forme de doses fixes comprenant un anti-acnéique et un antibiotique, qui sont stables au stockage à une température d'environ 40 °C et à une humidité relative d'environ 75 % pendant une période d'au moins 3 mois. Cette invention concerne, en particulier, des formulations topiques stables sous forme de doses fixes comprenant des quantités thérapeutiquement efficaces de (a) microsphères contenant de l'adapalène et (b) clindamycine, ainsi qu'un procédé pour leur préparation et leur utilisation pour le traitement de l'acné. |
| format | Patent |
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Cette invention concerne des formulations topiques stables sous forme de doses fixes comprenant un anti-acnéique et un antibiotique, qui sont stables au stockage à une température d'environ 40 °C et à une humidité relative d'environ 75 % pendant une période d'au moins 3 mois. Cette invention concerne, en particulier, des formulations topiques stables sous forme de doses fixes comprenant des quantités thérapeutiquement efficaces de (a) microsphères contenant de l'adapalène et (b) clindamycine, ainsi qu'un procédé pour leur préparation et leur utilisation pour le traitement de l'acné.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091210&DB=EPODOC&CC=WO&NR=2009116086A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091210&DB=EPODOC&CC=WO&NR=2009116086A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BHAMRE, NITIN BABULAL</creatorcontrib><creatorcontrib>CHAUDHARI, SUNIL SUDHAKAR</creatorcontrib><creatorcontrib>TRIVEDI, GIRISH RAMAKRISHNA</creatorcontrib><creatorcontrib>SHARMA, AKHILESH DAYANAND</creatorcontrib><creatorcontrib>DHUPPAD, ULHAS RAMESHCHANDRA</creatorcontrib><creatorcontrib>DONGRE, PRASHANT</creatorcontrib><title>TOPICAL FORMULATION COMPRISING ADAPALENE MICROSPHERES AND CLINDAMYCIN</title><description>The present invention relates to stable fixed dose topical formulations comprising an antiacne agent and an antibiotic, which exhibit storage stability at a temperature of about 40 °C and relative humidity of about 75 % for a period of at least 3 months. Particularly, the present invention relates to stable fixed dose topical formulations comprising therapeutically effective amounts of (a) adapalene-containing microspheres and (b) clindamycin, a process for their preparation thereof and their use for the treatment of acne.
Cette invention concerne des formulations topiques stables sous forme de doses fixes comprenant un anti-acnéique et un antibiotique, qui sont stables au stockage à une température d'environ 40 °C et à une humidité relative d'environ 75 % pendant une période d'au moins 3 mois. Cette invention concerne, en particulier, des formulations topiques stables sous forme de doses fixes comprenant des quantités thérapeutiquement efficaces de (a) microsphères contenant de l'adapalène et (b) clindamycine, ainsi qu'un procédé pour leur préparation et leur utilisation pour le traitement de l'acné.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAN8Q_wdHb0UXDzD_IN9XEM8fT3U3D29w0I8gz29HNXcHRxDHD0cfVzVfD1dA7yDw7wcA1yDVZw9HNRcPbx9HNx9I109vTjYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBgaWhoZmBhZmjsbGxKkCAF3LLUY</recordid><startdate>20091210</startdate><enddate>20091210</enddate><creator>BHAMRE, NITIN BABULAL</creator><creator>CHAUDHARI, SUNIL SUDHAKAR</creator><creator>TRIVEDI, GIRISH RAMAKRISHNA</creator><creator>SHARMA, AKHILESH DAYANAND</creator><creator>DHUPPAD, ULHAS RAMESHCHANDRA</creator><creator>DONGRE, PRASHANT</creator><scope>EVB</scope></search><sort><creationdate>20091210</creationdate><title>TOPICAL FORMULATION COMPRISING ADAPALENE MICROSPHERES AND CLINDAMYCIN</title><author>BHAMRE, NITIN BABULAL ; CHAUDHARI, SUNIL SUDHAKAR ; TRIVEDI, GIRISH RAMAKRISHNA ; SHARMA, AKHILESH DAYANAND ; DHUPPAD, ULHAS RAMESHCHANDRA ; DONGRE, PRASHANT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2009116086A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2009</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BHAMRE, NITIN BABULAL</creatorcontrib><creatorcontrib>CHAUDHARI, SUNIL SUDHAKAR</creatorcontrib><creatorcontrib>TRIVEDI, GIRISH RAMAKRISHNA</creatorcontrib><creatorcontrib>SHARMA, AKHILESH DAYANAND</creatorcontrib><creatorcontrib>DHUPPAD, ULHAS RAMESHCHANDRA</creatorcontrib><creatorcontrib>DONGRE, PRASHANT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BHAMRE, NITIN BABULAL</au><au>CHAUDHARI, SUNIL SUDHAKAR</au><au>TRIVEDI, GIRISH RAMAKRISHNA</au><au>SHARMA, AKHILESH DAYANAND</au><au>DHUPPAD, ULHAS RAMESHCHANDRA</au><au>DONGRE, PRASHANT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TOPICAL FORMULATION COMPRISING ADAPALENE MICROSPHERES AND CLINDAMYCIN</title><date>2009-12-10</date><risdate>2009</risdate><abstract>The present invention relates to stable fixed dose topical formulations comprising an antiacne agent and an antibiotic, which exhibit storage stability at a temperature of about 40 °C and relative humidity of about 75 % for a period of at least 3 months. Particularly, the present invention relates to stable fixed dose topical formulations comprising therapeutically effective amounts of (a) adapalene-containing microspheres and (b) clindamycin, a process for their preparation thereof and their use for the treatment of acne.
Cette invention concerne des formulations topiques stables sous forme de doses fixes comprenant un anti-acnéique et un antibiotique, qui sont stables au stockage à une température d'environ 40 °C et à une humidité relative d'environ 75 % pendant une période d'au moins 3 mois. Cette invention concerne, en particulier, des formulations topiques stables sous forme de doses fixes comprenant des quantités thérapeutiquement efficaces de (a) microsphères contenant de l'adapalène et (b) clindamycine, ainsi qu'un procédé pour leur préparation et leur utilisation pour le traitement de l'acné.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TOPICAL FORMULATION COMPRISING ADAPALENE MICROSPHERES AND CLINDAMYCIN |
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