FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE AS C-MET INHIBITORS
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and...
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| creator | LOHMAN, JULIA POTASHMAN, MICHELLE BAUER, DAVID HARMANGE, JEANRISTOPHE LEWIS, RICHARD T STEC, MARKIAN XI, NING YANG, KEVIN KIM, TAE-SEONG BOOKER, SHON HIRAI, SATOKO LIU, LONGBIN CHOQUETTE, DEBORAH PETERSON, EMILY, A BELLON, STEVEN ALBRECHT, BRIAN K NORMAN, MARK H HUNGATE, RANDALL W SPRINGER, STEPHANIE ROMERO, KARINA D'AMICO, ERIN SIEGMUND, AARON C BODE, CHRISTIANE M BOEZIO, ALESSANDRO COPELAND, KATRINA, W |
| description | Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Certains composés sont efficaces pour la prophylaxie et le traitement de maladies telles que les maladies médiées par HGF. L'invention englobe de nouveaux composés, des analogues, des promédicaments et des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement de maladies ou de troubles qui mettent en cause le cancer et similaires. La présente invention concerne également des procédés de fabrication de tels composés ainsi que des intermédiaires utiles dans de tels procédés. |
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Certains composés sont efficaces pour la prophylaxie et le traitement de maladies telles que les maladies médiées par HGF. L'invention englobe de nouveaux composés, des analogues, des promédicaments et des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement de maladies ou de troubles qui mettent en cause le cancer et similaires. La présente invention concerne également des procédés de fabrication de tels composés ainsi que des intermédiaires utiles dans de tels procédés.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091217&DB=EPODOC&CC=WO&NR=2009091374A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091217&DB=EPODOC&CC=WO&NR=2009091374A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LOHMAN, JULIA</creatorcontrib><creatorcontrib>POTASHMAN, MICHELLE</creatorcontrib><creatorcontrib>BAUER, DAVID</creatorcontrib><creatorcontrib>HARMANGE, JEANRISTOPHE</creatorcontrib><creatorcontrib>LEWIS, RICHARD T</creatorcontrib><creatorcontrib>STEC, MARKIAN</creatorcontrib><creatorcontrib>XI, NING</creatorcontrib><creatorcontrib>YANG, KEVIN</creatorcontrib><creatorcontrib>KIM, TAE-SEONG</creatorcontrib><creatorcontrib>BOOKER, SHON</creatorcontrib><creatorcontrib>HIRAI, SATOKO</creatorcontrib><creatorcontrib>LIU, LONGBIN</creatorcontrib><creatorcontrib>CHOQUETTE, DEBORAH</creatorcontrib><creatorcontrib>PETERSON, EMILY, A</creatorcontrib><creatorcontrib>BELLON, STEVEN</creatorcontrib><creatorcontrib>ALBRECHT, BRIAN K</creatorcontrib><creatorcontrib>NORMAN, MARK H</creatorcontrib><creatorcontrib>HUNGATE, RANDALL W</creatorcontrib><creatorcontrib>SPRINGER, STEPHANIE</creatorcontrib><creatorcontrib>ROMERO, KARINA</creatorcontrib><creatorcontrib>D'AMICO, ERIN</creatorcontrib><creatorcontrib>SIEGMUND, AARON C</creatorcontrib><creatorcontrib>BODE, CHRISTIANE M</creatorcontrib><creatorcontrib>BOEZIO, ALESSANDRO</creatorcontrib><creatorcontrib>COPELAND, KATRINA, W</creatorcontrib><title>FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE AS C-MET INHIBITORS</title><description>Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Certains composés sont efficaces pour la prophylaxie et le traitement de maladies telles que les maladies médiées par HGF. L'invention englobe de nouveaux composés, des analogues, des promédicaments et des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement de maladies ou de troubles qui mettent en cause le cancer et similaires. La présente invention concerne également des procédés de fabrication de tels composés ainsi que des intermédiaires utiles dans de tels procédés.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB1Cw12dVHwcA1xDfJ3jnT28XRWcHEN8gxzDPEMcw1WcPRzUfB1DfHwdwlW8HdTACpWcAxWcNYFiil4-nl4OnmG-AcF8zCwpiXmFKfyQmluBmU31xBnD93Ugvz41OKCxOTUvNSS-HB_IwMDSwNLQ2NzE0djY-JUAQAhOSzP</recordid><startdate>20091217</startdate><enddate>20091217</enddate><creator>LOHMAN, JULIA</creator><creator>POTASHMAN, MICHELLE</creator><creator>BAUER, DAVID</creator><creator>HARMANGE, JEANRISTOPHE</creator><creator>LEWIS, RICHARD T</creator><creator>STEC, MARKIAN</creator><creator>XI, NING</creator><creator>YANG, KEVIN</creator><creator>KIM, TAE-SEONG</creator><creator>BOOKER, SHON</creator><creator>HIRAI, SATOKO</creator><creator>LIU, LONGBIN</creator><creator>CHOQUETTE, DEBORAH</creator><creator>PETERSON, EMILY, A</creator><creator>BELLON, STEVEN</creator><creator>ALBRECHT, BRIAN K</creator><creator>NORMAN, MARK H</creator><creator>HUNGATE, RANDALL W</creator><creator>SPRINGER, STEPHANIE</creator><creator>ROMERO, KARINA</creator><creator>D'AMICO, ERIN</creator><creator>SIEGMUND, AARON C</creator><creator>BODE, CHRISTIANE M</creator><creator>BOEZIO, ALESSANDRO</creator><creator>COPELAND, KATRINA, W</creator><scope>EVB</scope></search><sort><creationdate>20091217</creationdate><title>FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE AS C-MET INHIBITORS</title><author>LOHMAN, JULIA ; 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The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Certains composés sont efficaces pour la prophylaxie et le traitement de maladies telles que les maladies médiées par HGF. L'invention englobe de nouveaux composés, des analogues, des promédicaments et des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement de maladies ou de troubles qui mettent en cause le cancer et similaires. La présente invention concerne également des procédés de fabrication de tels composés ainsi que des intermédiaires utiles dans de tels procédés.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE AS C-MET INHIBITORS |
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