GAMMA SECRETASE MODULATORS

The present invention provides compounds that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for p...

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Hauptverfasser:	NIXEY, THOMAS, CHEN, NING, LIU, QINGYIAN, ADAMS, JEFFREY A, QIAN, WENYUAN, YUAN, CHESTER CHENGUANG, PETERKIN, TANYA, CHEN, JIAN J, TEGLEY, CHRISTOPHER M, NCUBE, MQHELE, DEMORIN, FRENEL, ZHU, JIAWANG, KUNZ, ROXANNE, CHAVEZ, JR., FRANK, AMEGADZIE, ALBERT, HITCHCOCK, STEPHEN, HU, ESSA
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Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	NIXEY, THOMAS CHEN, NING LIU, QINGYIAN ADAMS, JEFFREY A QIAN, WENYUAN YUAN, CHESTER CHENGUANG PETERKIN, TANYA CHEN, JIAN J TEGLEY, CHRISTOPHER M NCUBE, MQHELE DEMORIN, FRENEL ZHU, JIAWANG KUNZ, ROXANNE CHAVEZ, JR., FRANK AMEGADZIE, ALBERT HITCHCOCK, STEPHEN HU, ESSA
description	The present invention provides compounds that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds. La présente invention concerne des composés qui sont des modulateurs de la gamma-sécrétase et qui sont, par conséquent, utiles pour le traitement de maladies, comme la maladie d'Alzheimer, qui peuvent être traitées par modulation de la gamma-sécrétase. L'invention concerne également des compositions pharmaceutiques qui contiennent de tels composés et des procédés de préparation de tels composés.
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	GAMMA SECRETASE MODULATORS
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