IMPROVED PROCESS FOR PREPARING DULOXETINE
The invention provides an improved process for preparing duloxetine. The invention provides an improved process for preparing duloxetine, efficiently and with good reaction rate, which is carried out in a homogeneous mixture, at a temperature lower than 80 °C, in which chiral integrity is preserved,...
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| creator | WINTER, STEPHEN BENEDICT DAVID |
| description | The invention provides an improved process for preparing duloxetine. The invention provides an improved process for preparing duloxetine, efficiently and with good reaction rate, which is carried out in a homogeneous mixture, at a temperature lower than 80 °C, in which chiral integrity is preserved, and neither sodium hydride nor potassium hydroxide is required.
L'invention concerne un procédé amélioré de préparation de duloxétine. L'invention concerne un procédé amélioré de préparation de duloxétine, de manière efficace et à une vitesse de réaction satisfaisante, qui est mis en oeuvre dans un mélange homogène, à une température inférieure à 80°C, dans lequel une intégrité chirale est préservée, et ne requérant ni l'utilisation d'hydrure de sodium, ni celle d'hydroxyde de potassium. |
| format | Patent |
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L'invention concerne un procédé amélioré de préparation de duloxétine. L'invention concerne un procédé amélioré de préparation de duloxétine, de manière efficace et à une vitesse de réaction satisfaisante, qui est mis en oeuvre dans un mélange homogène, à une température inférieure à 80°C, dans lequel une intégrité chirale est préservée, et ne requérant ni l'utilisation d'hydrure de sodium, ni celle d'hydroxyde de potassium.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090806&DB=EPODOC&CC=WO&NR=2009074883A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090806&DB=EPODOC&CC=WO&NR=2009074883A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WINTER, STEPHEN BENEDICT DAVID</creatorcontrib><title>IMPROVED PROCESS FOR PREPARING DULOXETINE</title><description>The invention provides an improved process for preparing duloxetine. The invention provides an improved process for preparing duloxetine, efficiently and with good reaction rate, which is carried out in a homogeneous mixture, at a temperature lower than 80 °C, in which chiral integrity is preserved, and neither sodium hydride nor potassium hydroxide is required.
L'invention concerne un procédé amélioré de préparation de duloxétine. L'invention concerne un procédé amélioré de préparation de duloxétine, de manière efficace et à une vitesse de réaction satisfaisante, qui est mis en oeuvre dans un mélange homogène, à une température inférieure à 80°C, dans lequel une intégrité chirale est préservée, et ne requérant ni l'utilisation d'hydrure de sodium, ni celle d'hydroxyde de potassium.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND09A0I8g9zdVEAUs6uwcEKbv5BQLZrgGOQp5-7gkuoj3-Ea4innysPA2taYk5xKi-U5mZQdnMNcfbQTS3Ij08tLkhMTs1LLYkP9zcyMLA0MDexsDB2NDYmThUA4Polqw</recordid><startdate>20090806</startdate><enddate>20090806</enddate><creator>WINTER, STEPHEN BENEDICT DAVID</creator><scope>EVB</scope></search><sort><creationdate>20090806</creationdate><title>IMPROVED PROCESS FOR PREPARING DULOXETINE</title><author>WINTER, STEPHEN BENEDICT DAVID</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2009074883A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2009</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>WINTER, STEPHEN BENEDICT DAVID</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WINTER, STEPHEN BENEDICT DAVID</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IMPROVED PROCESS FOR PREPARING DULOXETINE</title><date>2009-08-06</date><risdate>2009</risdate><abstract>The invention provides an improved process for preparing duloxetine. The invention provides an improved process for preparing duloxetine, efficiently and with good reaction rate, which is carried out in a homogeneous mixture, at a temperature lower than 80 °C, in which chiral integrity is preserved, and neither sodium hydride nor potassium hydroxide is required.
L'invention concerne un procédé amélioré de préparation de duloxétine. L'invention concerne un procédé amélioré de préparation de duloxétine, de manière efficace et à une vitesse de réaction satisfaisante, qui est mis en oeuvre dans un mélange homogène, à une température inférieure à 80°C, dans lequel une intégrité chirale est préservée, et ne requérant ni l'utilisation d'hydrure de sodium, ni celle d'hydroxyde de potassium.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | IMPROVED PROCESS FOR PREPARING DULOXETINE |
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