MULTI- COMPONENT L2 VACCINE FOR PREVENTION OF HUMAN PAPILLOMAVIRUS INFECTION

Embodiments of the invention are directed to methods and compositions for generating an antibody response against HPV epitopes using multi-component vaccines. One such multi-component vaccine requires a T cell helper component and a toll-like receptor (TLR) agonist. In one embodiment, the inventors...

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Hauptverfasser: GAMBHIRA, RATISH, ALPHS, HANNAH, H, RODEN, RICHARD, B.S
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creator GAMBHIRA, RATISH
ALPHS, HANNAH, H
RODEN, RICHARD, B.S
description Embodiments of the invention are directed to methods and compositions for generating an antibody response against HPV epitopes using multi-component vaccines. One such multi-component vaccine requires a T cell helper component and a toll-like receptor (TLR) agonist. In one embodiment, the inventors described a lipopeptide composition comprising an HPV L2 epitope. L'invention concerne des procédés et des compositions pour générer une réponse d'anticorps à des épitopes d'HPV utilisant des vaccins multicomposants. Un tel vaccin multicomposant requiert un composant de lymphocyte T auxiliaire et un agoniste de récepteur de type péage (TLR). Dans un mode de réalisation, les inventeurs ont décrit une composition de lipopeptide comprenant un épitope L2 de HPV.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title MULTI- COMPONENT L2 VACCINE FOR PREVENTION OF HUMAN PAPILLOMAVIRUS INFECTION
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