BIOPOLYMER SEQUENCING BY HYBRIDIZATION OF PROBES TO FORM TERNARY COMPLEXES AND VARIABLE RANGE ALIGNMENT

Methods for sequencing a biopolymer by forming local ternary complexes along the length of the double- stranded biopolymer target molecule using one or more probes and obtaining information about the location of the probe(s) using a detector. These methods offer particular advantage when implemented...

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Hauptverfasser: GOLDSTEIN, PETER, PREPARATA, FRANCO, OLIVER, JOHN, BREADY, BARRETT
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creator GOLDSTEIN, PETER
PREPARATA, FRANCO
OLIVER, JOHN
BREADY, BARRETT
description Methods for sequencing a biopolymer by forming local ternary complexes along the length of the double- stranded biopolymer target molecule using one or more probes and obtaining information about the location of the probe(s) using a detector. These methods offer particular advantage when implemented with nanopore (including micropore) detection systems. L'invention concerne des procédés de séquençage d'un biopolymère par la formation de complexes ternaires locaux sur la longueur de la molécule cible de biopolymère à double brin en utilisant une ou plusieurs sondes et l'obtention d'informations sur l'emplacement de la ou des secondes en utilisant un détecteur. Ces procédés offrent un avantage particulier lorsqu'ils sont mis en oevre avec des systèmes de détection de nanopore (y compris micropore).
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title BIOPOLYMER SEQUENCING BY HYBRIDIZATION OF PROBES TO FORM TERNARY COMPLEXES AND VARIABLE RANGE ALIGNMENT
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