METHODS AND COMPOSITIONS FOR DELIVERY OF GROWTH FACTOR TO FIBROUS CONNECTIVE TISSUE
The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide ha...
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| creator | JUZUMIENE, DALIA, IZOLDA CHEN, YUCHEN BUEHRER, BENJAMIN, MARCUS NAIR, SHRIKUMAR, AMBUJAKSHAN HAMILTON, PAUL, THEODORE |
| description | The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions.
La présente invention concerne une composition de peptides pour localiser, par des moyens non covalents, un facteur de croissance induisant un tissu conjonctif fibreux, sur une surface d'un implant, la composition comprenant un peptide ayant une affinité de liaison pour un matériau de surface d'un implant, couplé à un peptide ayant une affinité de liaison pour un facteur de croissance induisant un tissu conjonctif fibreux. L'invention concerne des procédés pour administrer le facteur de croissance induisant un tissu conjonctif fibreux GDF-7 en une quantité efficace pour activer la réparation du tissu conjonctif fibreux et la formation de tissu conjonctif fibreux. Elle concerne également des procédés d'application de la composition de peptides sur un implant en mettant la composition en contact avec une surface de l'implant; et des kits comprenant les compositions. |
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La présente invention concerne une composition de peptides pour localiser, par des moyens non covalents, un facteur de croissance induisant un tissu conjonctif fibreux, sur une surface d'un implant, la composition comprenant un peptide ayant une affinité de liaison pour un matériau de surface d'un implant, couplé à un peptide ayant une affinité de liaison pour un facteur de croissance induisant un tissu conjonctif fibreux. L'invention concerne des procédés pour administrer le facteur de croissance induisant un tissu conjonctif fibreux GDF-7 en une quantité efficace pour activer la réparation du tissu conjonctif fibreux et la formation de tissu conjonctif fibreux. Elle concerne également des procédés d'application de la composition de peptides sur un implant en mettant la composition en contact avec une surface de l'implant; et des kits comprenant les compositions.</description><language>eng ; fre</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROSTHESES ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091230&DB=EPODOC&CC=WO&NR=2009032943A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091230&DB=EPODOC&CC=WO&NR=2009032943A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JUZUMIENE, DALIA, IZOLDA</creatorcontrib><creatorcontrib>CHEN, YUCHEN</creatorcontrib><creatorcontrib>BUEHRER, BENJAMIN, MARCUS</creatorcontrib><creatorcontrib>NAIR, SHRIKUMAR, AMBUJAKSHAN</creatorcontrib><creatorcontrib>HAMILTON, PAUL, THEODORE</creatorcontrib><title>METHODS AND COMPOSITIONS FOR DELIVERY OF GROWTH FACTOR TO FIBROUS CONNECTIVE TISSUE</title><description>The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions.
La présente invention concerne une composition de peptides pour localiser, par des moyens non covalents, un facteur de croissance induisant un tissu conjonctif fibreux, sur une surface d'un implant, la composition comprenant un peptide ayant une affinité de liaison pour un matériau de surface d'un implant, couplé à un peptide ayant une affinité de liaison pour un facteur de croissance induisant un tissu conjonctif fibreux. L'invention concerne des procédés pour administrer le facteur de croissance induisant un tissu conjonctif fibreux GDF-7 en une quantité efficace pour activer la réparation du tissu conjonctif fibreux et la formation de tissu conjonctif fibreux. Elle concerne également des procédés d'application de la composition de peptides sur un implant en mettant la composition en contact avec une surface de l'implant; et des kits comprenant les compositions.</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROSTHESES</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi7sKwjAUQLM4iPoPF5yF0Lh0rHmYgM2V3NsWp1IkTqKF-v-YwQ9wOsM5Zy2otezREDTRgMb2ihQ4YCRwmMDYS-htugE6OCcc2INrNBfDCC6cEnZUrhit5hICB6LObsXqMT2XvPtxI_bOsvaHPL_HvMzTPb_yZxywkrKWqqqPqlHqv-oL5S4xHg</recordid><startdate>20091230</startdate><enddate>20091230</enddate><creator>JUZUMIENE, DALIA, IZOLDA</creator><creator>CHEN, YUCHEN</creator><creator>BUEHRER, BENJAMIN, MARCUS</creator><creator>NAIR, SHRIKUMAR, AMBUJAKSHAN</creator><creator>HAMILTON, PAUL, THEODORE</creator><scope>EVB</scope></search><sort><creationdate>20091230</creationdate><title>METHODS AND COMPOSITIONS FOR DELIVERY OF GROWTH FACTOR TO FIBROUS CONNECTIVE TISSUE</title><author>JUZUMIENE, DALIA, IZOLDA ; CHEN, YUCHEN ; BUEHRER, BENJAMIN, MARCUS ; NAIR, SHRIKUMAR, AMBUJAKSHAN ; HAMILTON, PAUL, THEODORE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2009032943A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2009</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROSTHESES</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>JUZUMIENE, DALIA, IZOLDA</creatorcontrib><creatorcontrib>CHEN, YUCHEN</creatorcontrib><creatorcontrib>BUEHRER, BENJAMIN, MARCUS</creatorcontrib><creatorcontrib>NAIR, SHRIKUMAR, AMBUJAKSHAN</creatorcontrib><creatorcontrib>HAMILTON, PAUL, THEODORE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JUZUMIENE, DALIA, IZOLDA</au><au>CHEN, YUCHEN</au><au>BUEHRER, BENJAMIN, MARCUS</au><au>NAIR, SHRIKUMAR, AMBUJAKSHAN</au><au>HAMILTON, PAUL, THEODORE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS AND COMPOSITIONS FOR DELIVERY OF GROWTH FACTOR TO FIBROUS CONNECTIVE TISSUE</title><date>2009-12-30</date><risdate>2009</risdate><abstract>The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions.
La présente invention concerne une composition de peptides pour localiser, par des moyens non covalents, un facteur de croissance induisant un tissu conjonctif fibreux, sur une surface d'un implant, la composition comprenant un peptide ayant une affinité de liaison pour un matériau de surface d'un implant, couplé à un peptide ayant une affinité de liaison pour un facteur de croissance induisant un tissu conjonctif fibreux. L'invention concerne des procédés pour administrer le facteur de croissance induisant un tissu conjonctif fibreux GDF-7 en une quantité efficace pour activer la réparation du tissu conjonctif fibreux et la formation de tissu conjonctif fibreux. Elle concerne également des procédés d'application de la composition de peptides sur un implant en mettant la composition en contact avec une surface de l'implant; et des kits comprenant les compositions.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROSTHESES TREATMENT OR PROTECTION OF EYES OR EARS |
| title | METHODS AND COMPOSITIONS FOR DELIVERY OF GROWTH FACTOR TO FIBROUS CONNECTIVE TISSUE |
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