LIQUID DOSAGE FORMS OF FLUOROQUINOLONE ANTIBIOTICS OR SALT THEREOF FOR OPHTHALMIC, OTIC AND NASAL ADMINISTRATION

The present invention relates to stable solutions suitable for ophthalmic, otic or nasal administration that include fluoroquinolone antibiotic or salts thereof and amino acid, optionally in combination with one or more drugs for the treatment of bacterial infections. The invention further provides...

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Hauptverfasser: MAINDE, CHANDRASHEKHAR, NAGORI, RAJENDRA, NANDLAL, ACHLIYA, GIRISH, SHANTILAL, BORA, SURESH, PARASMAL
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creator MAINDE, CHANDRASHEKHAR
NAGORI, RAJENDRA, NANDLAL
ACHLIYA, GIRISH, SHANTILAL
BORA, SURESH, PARASMAL
description The present invention relates to stable solutions suitable for ophthalmic, otic or nasal administration that include fluoroquinolone antibiotic or salts thereof and amino acid, optionally in combination with one or more drugs for the treatment of bacterial infections. The invention further provides stable solutions suitable for ophthalmic, otic, or nasal administration that include nadifloxacin and pharmaceutically acceptable salts thereof. The invention also relates to processes for the preparation of the stable solutions. La présente invention porte sur des solutions stables pour administration ophtalmique, otique ou nasale. Les solutions contiennent un antibiotique fluoroquinolone ou des sels de celui-ci et un acide aminé, facultativement en combinaison avec un ou plusieurs médicaments pour le traitement d'infections bactériennes. L'invention porte en outre sur des solutions stables pour administration ophtalmique, otique ou nasale qui contiennent de la nadifloxacine et des sels pharmaceutiquement acceptables de celle-ci. L'invention porte également sur des procédés de préparation desdites solutions stables.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title LIQUID DOSAGE FORMS OF FLUOROQUINOLONE ANTIBIOTICS OR SALT THEREOF FOR OPHTHALMIC, OTIC AND NASAL ADMINISTRATION
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