TARGETED OXYGEN DELIVERY VIA INTRAVENOUS OR INTRA-ARTERIAL INFUSION OF OXYGENATED POLYMERIZED HEMOGLOBIN SOLUTIONS

A method of delivering oxygen to a tissue, a blood vessel, an organ, or a region of an organ, under an ischemic condition, or prophylactically preventing occurrence of an ischemic condition, of a subject, comprising the step of administering to the subject an oxygenated hemoglobin solution, wherein...

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Hauptverfasser: LACCETTI, ANTHONY, J, DUBE, GREGORY, P, BAQAI, JAVED, ZAFIRELIS, W., ZAFIRIS
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creator LACCETTI, ANTHONY, J
DUBE, GREGORY, P
BAQAI, JAVED
ZAFIRELIS, W., ZAFIRIS
description A method of delivering oxygen to a tissue, a blood vessel, an organ, or a region of an organ, under an ischemic condition, or prophylactically preventing occurrence of an ischemic condition, of a subject, comprising the step of administering to the subject an oxygenated hemoglobin solution, wherein the oxygenated hemoglobin solution includes polymerized hemoglobin, and wherein about 80% by weight, or greater, of the polymerized hemoglobin is oxyhemoglobin. L'invention porte sur un procédé de distribution d'oxygène à un tissu, un vaisseau sanguin, un organe ou une région d'un organe d'un sujet, dans une condition ischémique, ou de prévention de manière prophylactique de l'apparition d'une condition ischémique. Ce procédé comprend l'étape consistant à administrer au sujet une solution d'hémoglobine oxygénée, la solution d'hémoglobine oxygénée comprenant de l'hémoglobine polymérisée, et environ 80 % en poids, ou plus, de l'hémoglobine polymérisée étant de l'oxyhémoglobine.
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L'invention porte sur un procédé de distribution d'oxygène à un tissu, un vaisseau sanguin, un organe ou une région d'un organe d'un sujet, dans une condition ischémique, ou de prévention de manière prophylactique de l'apparition d'une condition ischémique. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TARGETED OXYGEN DELIVERY VIA INTRAVENOUS OR INTRA-ARTERIAL INFUSION OF OXYGENATED POLYMERIZED HEMOGLOBIN SOLUTIONS
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