COMBINED USE OF EGF PATHWAY INHIBITORS AND DIFFERENTIATION PROMOTING COMPOUNDS
The present invention is a pharmaceutical composition and method for its use in the treatment of chronic inflammatory skin diseases such as psoriasis. The pharmaceutical composition combines an inhibitor of the EGF receptor signaling pathway with an agent that promotes cell differentiation. This pha...
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| creator | SUTTER, CARRIE H SUTTER, THOMAS R |
| description | The present invention is a pharmaceutical composition and method for its use in the treatment of chronic inflammatory skin diseases such as psoriasis. The pharmaceutical composition combines an inhibitor of the EGF receptor signaling pathway with an agent that promotes cell differentiation. This pharmaceutical composition may be administered orally or topically, and results in superior treatment of chronic inflammatory skin diseases than methods presently in use.
L'invention concerne une composition pharmaceutique et un procédé d'utilisation de celle-ci dans le traitement de maladies inflammatoires chroniques de la peau telles que le psoriasis. Cette composition pharmaceutique combine un inhibiteur de la voie de signalisation des récepteurs d'EGF avec un agent qui active la différenciation cellulaire. Cette composition pharmaceutique peut être administrée par voie orale ou topique, et forme un traitement supérieur de maladies inflammatoires chroniques de la peau par rapport aux traitements utilisés actuellement. |
| format | Patent |
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L'invention concerne une composition pharmaceutique et un procédé d'utilisation de celle-ci dans le traitement de maladies inflammatoires chroniques de la peau telles que le psoriasis. Cette composition pharmaceutique combine un inhibiteur de la voie de signalisation des récepteurs d'EGF avec un agent qui active la différenciation cellulaire. Cette composition pharmaceutique peut être administrée par voie orale ou topique, et forme un traitement supérieur de maladies inflammatoires chroniques de la peau par rapport aux traitements utilisés actuellement.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090430&DB=EPODOC&CC=WO&NR=2008132608A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090430&DB=EPODOC&CC=WO&NR=2008132608A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SUTTER, CARRIE H</creatorcontrib><creatorcontrib>SUTTER, THOMAS R</creatorcontrib><title>COMBINED USE OF EGF PATHWAY INHIBITORS AND DIFFERENTIATION PROMOTING COMPOUNDS</title><description>The present invention is a pharmaceutical composition and method for its use in the treatment of chronic inflammatory skin diseases such as psoriasis. The pharmaceutical composition combines an inhibitor of the EGF receptor signaling pathway with an agent that promotes cell differentiation. This pharmaceutical composition may be administered orally or topically, and results in superior treatment of chronic inflammatory skin diseases than methods presently in use.
L'invention concerne une composition pharmaceutique et un procédé d'utilisation de celle-ci dans le traitement de maladies inflammatoires chroniques de la peau telles que le psoriasis. Cette composition pharmaceutique combine un inhibiteur de la voie de signalisation des récepteurs d'EGF avec un agent qui active la différenciation cellulaire. Cette composition pharmaceutique peut être administrée par voie orale ou topique, et forme un traitement supérieur de maladies inflammatoires chroniques de la peau par rapport aux traitements utilisés actuellement.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNzLEKwjAQgOEsDqK-w4GzEBuQrmmTNDf0LiQpxakUiZNoob4_OvgATv_y8W8Ftdw3SNbAkCywA9s5CDr7UV8ByWODmWMCTQYMOmejpYw6IxOEyD1npA6-k8ADmbQXm_v8WMvh1504OptbfyrLayrrMt_Ks7ynkSsp67OqLrLWSv2nPtWjL5g</recordid><startdate>20090430</startdate><enddate>20090430</enddate><creator>SUTTER, CARRIE H</creator><creator>SUTTER, THOMAS R</creator><scope>EVB</scope></search><sort><creationdate>20090430</creationdate><title>COMBINED USE OF EGF PATHWAY INHIBITORS AND DIFFERENTIATION PROMOTING COMPOUNDS</title><author>SUTTER, CARRIE H ; SUTTER, THOMAS R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2008132608A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2009</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SUTTER, CARRIE H</creatorcontrib><creatorcontrib>SUTTER, THOMAS R</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SUTTER, CARRIE H</au><au>SUTTER, THOMAS R</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMBINED USE OF EGF PATHWAY INHIBITORS AND DIFFERENTIATION PROMOTING COMPOUNDS</title><date>2009-04-30</date><risdate>2009</risdate><abstract>The present invention is a pharmaceutical composition and method for its use in the treatment of chronic inflammatory skin diseases such as psoriasis. The pharmaceutical composition combines an inhibitor of the EGF receptor signaling pathway with an agent that promotes cell differentiation. This pharmaceutical composition may be administered orally or topically, and results in superior treatment of chronic inflammatory skin diseases than methods presently in use.
L'invention concerne une composition pharmaceutique et un procédé d'utilisation de celle-ci dans le traitement de maladies inflammatoires chroniques de la peau telles que le psoriasis. Cette composition pharmaceutique combine un inhibiteur de la voie de signalisation des récepteurs d'EGF avec un agent qui active la différenciation cellulaire. Cette composition pharmaceutique peut être administrée par voie orale ou topique, et forme un traitement supérieur de maladies inflammatoires chroniques de la peau par rapport aux traitements utilisés actuellement.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | COMBINED USE OF EGF PATHWAY INHIBITORS AND DIFFERENTIATION PROMOTING COMPOUNDS |
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