METHOD OF MANUFACTURING 1-(2-DEOXY-ALPHA-D-ERYTHRO-PENTOFURANOSYL)-5-AZACYTOSINE
This invention relates to a method of manufacturing 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine by the treatment of protected alkyl or aralkyl 2-deoxy-D-erythro-pentofuranoside with silylated 5-azacytosine in the presence of Lewis acid and subsequent removal the protecting groups. L...
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| creator | PISKALA, ALOIS HOLY, ANTONIN OTMAR, MIROSLAV |
| description | This invention relates to a method of manufacturing 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine by the treatment of protected alkyl or aralkyl 2-deoxy-D-erythro-pentofuranoside with silylated 5-azacytosine in the presence of Lewis acid and subsequent removal the protecting groups.
L'invention concerne un procédé de fabrication de 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine lorsque l'on traite 2-deoxy-D-erythro-pentofuranoside alkyle ou aralkyle protégé avec 5-azacytosine syliée en présence d'acide de Lewis et que l'on élimine ensuite les groupes de protection. |
| format | Patent |
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L'invention concerne un procédé de fabrication de 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine lorsque l'on traite 2-deoxy-D-erythro-pentofuranoside alkyle ou aralkyle protégé avec 5-azacytosine syliée en présence d'acide de Lewis et que l'on élimine ensuite les groupes de protection.</description><language>eng ; fre</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; SUGARS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090319&DB=EPODOC&CC=WO&NR=2008101448A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090319&DB=EPODOC&CC=WO&NR=2008101448A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PISKALA, ALOIS</creatorcontrib><creatorcontrib>HOLY, ANTONIN</creatorcontrib><creatorcontrib>OTMAR, MIROSLAV</creatorcontrib><title>METHOD OF MANUFACTURING 1-(2-DEOXY-ALPHA-D-ERYTHRO-PENTOFURANOSYL)-5-AZACYTOSINE</title><description>This invention relates to a method of manufacturing 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine by the treatment of protected alkyl or aralkyl 2-deoxy-D-erythro-pentofuranoside with silylated 5-azacytosine in the presence of Lewis acid and subsequent removal the protecting groups.
L'invention concerne un procédé de fabrication de 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine lorsque l'on traite 2-deoxy-D-erythro-pentofuranoside alkyle ou aralkyle protégé avec 5-azacytosine syliée en présence d'acide de Lewis et que l'on élimine ensuite les groupes de protection.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAjwdQ3x8HdR8HdT8HX0C3VzdA4JDfL0c1cw1NUw0nVx9Y-I1HX0CfBw1HXRdQ2KDPEI8tcNcPUL8XcLDXL08w-O9NHUNdV1jHJ0jgzxD_b0c-VhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGBhaGBoYmJhaOJsbEqQIAHyAv8w</recordid><startdate>20090319</startdate><enddate>20090319</enddate><creator>PISKALA, ALOIS</creator><creator>HOLY, ANTONIN</creator><creator>OTMAR, MIROSLAV</creator><scope>EVB</scope></search><sort><creationdate>20090319</creationdate><title>METHOD OF MANUFACTURING 1-(2-DEOXY-ALPHA-D-ERYTHRO-PENTOFURANOSYL)-5-AZACYTOSINE</title><author>PISKALA, ALOIS ; HOLY, ANTONIN ; OTMAR, MIROSLAV</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2008101448A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2009</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>PISKALA, ALOIS</creatorcontrib><creatorcontrib>HOLY, ANTONIN</creatorcontrib><creatorcontrib>OTMAR, MIROSLAV</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PISKALA, ALOIS</au><au>HOLY, ANTONIN</au><au>OTMAR, MIROSLAV</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF MANUFACTURING 1-(2-DEOXY-ALPHA-D-ERYTHRO-PENTOFURANOSYL)-5-AZACYTOSINE</title><date>2009-03-19</date><risdate>2009</risdate><abstract>This invention relates to a method of manufacturing 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine by the treatment of protected alkyl or aralkyl 2-deoxy-D-erythro-pentofuranoside with silylated 5-azacytosine in the presence of Lewis acid and subsequent removal the protecting groups.
L'invention concerne un procédé de fabrication de 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-azacytosine lorsque l'on traite 2-deoxy-D-erythro-pentofuranoside alkyle ou aralkyle protégé avec 5-azacytosine syliée en présence d'acide de Lewis et que l'on élimine ensuite les groupes de protection.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS |
| title | METHOD OF MANUFACTURING 1-(2-DEOXY-ALPHA-D-ERYTHRO-PENTOFURANOSYL)-5-AZACYTOSINE |
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