METHODS FOR PREPARING ESZOPICLONE

Methods for the preparation of crystalline eszopiclone free base in water, in the absence of organic solvents, are provided. The methods are more environmentally acceptable than prior art methods, and produce eszopiclone free base essentially free of residual organic solvent. L'invention concer...

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Hauptverfasser: MENDELOVICI, MARIOARA, RAMATY, REVITAL, FINKELSTEIN, NINA, MAINFELD, ALEX
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RAMATY, REVITAL
FINKELSTEIN, NINA
MAINFELD, ALEX
description Methods for the preparation of crystalline eszopiclone free base in water, in the absence of organic solvents, are provided. The methods are more environmentally acceptable than prior art methods, and produce eszopiclone free base essentially free of residual organic solvent. L'invention concerne des procédés pour la préparation de base libre d'eszopiclone cristalline dans l'eau, en l'absence de solvants organiques. Les procédés sont plus acceptables d'un point de vue environnemental que les procédés de l'art antérieur, et produisent une base libre d'eszopiclone essentiellement dépourvue de solvant organique résiduel.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title METHODS FOR PREPARING ESZOPICLONE
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