USE OF 5-HT6 ANTAGONISTS TO PREVENT RELAPSE INTO ADDICTION
The invention relates to a novel use of compounds and pharmaceutically acceptable salts thereof, which are 5-HT6 antagonists. These compounds are useful for the preparation of medicaments for preventing relapse into addiction, in particular relapse into addiction to substances of abuse, including op...
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| creator | DE BRUIN, NATASJA M.W.J WIJNEN, JOHAN VAN LOEVEZIJN, ARNOLD HERREMANS, ARNOLDUS H.J KRUSE, CORNELIS G |
| description | The invention relates to a novel use of compounds and pharmaceutically acceptable salts thereof, which are 5-HT6 antagonists. These compounds are useful for the preparation of medicaments for preventing relapse into addiction, in particular relapse into addiction to substances of abuse, including opiates, hallucinogens, inhalants, phencyclidine, amphetamines, cocaine, cannabis, nicotine, and alcohol, into relapse to addiction to certain medicines, including sedatives, hypnotics and anxiolytics, and into relapse to certain addictive behaviors, including gambling.
L'invention porte sur une nouvelle utilisation de composés et de sels pharmaceutiquement acceptables de ceux-ci, qui sont des antagonistes de 5-HT6. Ces composés sont utiles pour la préparation de médicaments de prévention d'une récidive d'addiction, en particulier une récidive d'addiction à l'usage de substances toxiques (opiacés, hallucinogènes, produits pour inhalation, phencyclidine, amphétamines, cocaïne, cannabis, nicotine et alcool) ainsi qu'à certains médicaments (sédatifs, hypnotiques et anxiolytiques), et de prévention d'une rechute dans certains comportements addictifs comme le jeu. |
| format | Patent |
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L'invention porte sur une nouvelle utilisation de composés et de sels pharmaceutiquement acceptables de ceux-ci, qui sont des antagonistes de 5-HT6. Ces composés sont utiles pour la préparation de médicaments de prévention d'une récidive d'addiction, en particulier une récidive d'addiction à l'usage de substances toxiques (opiacés, hallucinogènes, produits pour inhalation, phencyclidine, amphétamines, cocaïne, cannabis, nicotine et alcool) ainsi qu'à certains médicaments (sédatifs, hypnotiques et anxiolytiques), et de prévention d'une rechute dans certains comportements addictifs comme le jeu.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | USE OF 5-HT6 ANTAGONISTS TO PREVENT RELAPSE INTO ADDICTION |
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