INHIBITION OF INVERTEBRATES USING LIGANDS THAT MODULATE ECDYSONE RECEPTORS

The present invention relates to the use of N-substituted ?-methylene ?-lactams as non- steroidal ligands for modulating ecdysone receptors generally (resulting in controlled insect growth) and, in particular, ecdysone receptors of the Australian blowfly, Lucilia cuprina and the sheep body louse Bov...

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Hauptverfasser: LIEPA, ANDRIS JURIS, TURNER, KATHLEEN ANNE, JOHNSON, WYNONA MARGUERITE
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TURNER, KATHLEEN ANNE
JOHNSON, WYNONA MARGUERITE
description The present invention relates to the use of N-substituted ?-methylene ?-lactams as non- steroidal ligands for modulating ecdysone receptors generally (resulting in controlled insect growth) and, in particular, ecdysone receptors of the Australian blowfly, Lucilia cuprina and the sheep body louse Bovicola ovis. The present invention further relates to novel N-substituted ?-methylene ?-lactams. These compounds are useful as insecticides or as lead compounds for the development of insecticides. The compounds are also useful as effectors for ecdysone switches. La présente invention concerne l'utilisation de ?-méthylène ?-lactames N-substituées en tant que ligands non stéroïdiens permettant de moduler les récepteurs de l'ecdysone en général (ce qui permet de contrôler la croissance des insectes), et en particulier les récepteurs de l'ecdysone de la calliphore australienne, Lucilia cuprina, et du pou du mouton, Bovicola ovis. L'invention a également trait à de nouvelles ?-méthylène ?-lactames N-substituées. Lesdits composés sont utiles en tant qu'insecticides ou en tant que têtes de série permettant l'élaboration d'insecticides. Les composés sont également utiles en tant qu'effecteurs pour les commutateurs de l'ecdysone.
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subjects AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMISTRY
FISHING
FORESTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HUNTING
METALLURGY
ORGANIC CHEMISTRY
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
title INHIBITION OF INVERTEBRATES USING LIGANDS THAT MODULATE ECDYSONE RECEPTORS
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