INHIBITING TRANSLATION OF ABRERRANT DNMT3B TRANSCRIPTS IN CANCER CELLS USING INHIBITORY NUCLEIC ACIDS

The present invention provides new methods of inhibiting aberrant DNA methyltransferase 3B (DNMT3B) transcripts containing abnormal splicing. Inhibitory nucleic acids, such as interfering RNAs and antisense molecules target improperly retained introns, thereby selectively inhibiting aberrant transcr...

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Bibliographische Detailangaben

Hauptverfasser:	OSTLER, KELLY, R, GODLEY, LUCY, A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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