INDAZOLE DERIVATIVES AS MODULATORS OF INTERLEUKIN- 1 RECEPTOR-ASSOCIATED KINASE

The present invention relates to modulators of IRAK kinases of formula (I) and provides compositions comprising such modulators, as well as methods therewith for treating IRAK- mediated or IRAK -associated conditions or diseases. La présente invention concerne des modulateurs des kinases IRAK (Inter...

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Hauptverfasser: CONLAN, PATRICK, GUCKIAN, KEVIN, CHAN, TIMOTHY, JEWELL, CHARLES, LIN, EDWARD, YIN-SHIANG
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creator CONLAN, PATRICK
GUCKIAN, KEVIN
CHAN, TIMOTHY
JEWELL, CHARLES
LIN, EDWARD, YIN-SHIANG
description The present invention relates to modulators of IRAK kinases of formula (I) and provides compositions comprising such modulators, as well as methods therewith for treating IRAK- mediated or IRAK -associated conditions or diseases. La présente invention concerne des modulateurs des kinases IRAK (Interleukin-1 Receptor-Associated Kinase) et des compositions comprenant de tels modulateurs, ainsi que des procédés permettant de traiter des affections ou des maladies induites par l'IRAK ou associées à l'IRAK.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INDAZOLE DERIVATIVES AS MODULATORS OF INTERLEUKIN- 1 RECEPTOR-ASSOCIATED KINASE
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