INDAZOLE DERIVATIVES AS MODULATORS OF INTERLEUKIN- 1 RECEPTOR-ASSOCIATED KINASE

The present invention relates to modulators of IRAK kinases of formula (I) and provides compositions comprising such modulators, as well as methods therewith for treating IRAK- mediated or IRAK -associated conditions or diseases. La présente invention concerne des modulateurs des kinases IRAK (Inter...

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Bibliographische Detailangaben
Hauptverfasser:	CONLAN, PATRICK, GUCKIAN, KEVIN, CHAN, TIMOTHY, JEWELL, CHARLES, LIN, EDWARD, YIN-SHIANG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to modulators of IRAK kinases of formula (I) and provides compositions comprising such modulators, as well as methods therewith for treating IRAK- mediated or IRAK -associated conditions or diseases. La présente invention concerne des modulateurs des kinases IRAK (Interleukin-1 Receptor-Associated Kinase) et des compositions comprenant de tels modulateurs, ainsi que des procédés permettant de traiter des affections ou des maladies induites par l'IRAK ou associées à l'IRAK.