STEAROYL COA DESATURASE INHIBITORS
The present invention relates to novel Stearoyl CoA desaturase (SCD) inhibitors and uses thereof for treating diseases, conditions and/or disorders modulated by a Stearoyl CoA desaturase enzyme. The SCD inihibitors have the formula (I) or a pharmaceutically acceptable salt thereof, a pharmaceuticall...
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creator | LINGAM, V.S. PRASADA RAO KHAIRATKAR-JOSHI, NEELIMA THOMAS, ABRAHAM CHAUDHARI, SACHIN, S SHAH, DAISY MANISH |
description | The present invention relates to novel Stearoyl CoA desaturase (SCD) inhibitors and uses thereof for treating diseases, conditions and/or disorders modulated by a Stearoyl CoA desaturase enzyme. The SCD inihibitors have the formula (I) or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable ester thereof, a tautomer thereof, a regioisomer thereof, a stereoisomer thereof, a enantiomer thereof, a diastereomer thereof, a polymorph thereof, or a pharmaceutically acceptable solvate thereof, wherein the variables are as described herein.
La présente invention concerne de nouveaux inhibiteurs de la Stéaroyl CoA désaturase (SCD) et leurs utilisations pour traiter des maladies, états et/ou troubles modulés par une enzyme Stéaroyl CoA désaturase. Les inhibiteurs de la SCD ont une certaine formule ou un sel pharmaceutiquement acceptable de celle-ci, un ester pharmaceutiquement acceptable de celle-ci, un tautomère de celle-ci, un régioisomère de celle-ci, un stéréoisomère de celle-ci, un énantiomère de celle-ci, un diastéréomère de celle-ci, un polymorphe de celle-ci ou un solvate pharmaceutiquement acceptable de celle-ci, les variables étant telles que décrites présentement. |
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La présente invention concerne de nouveaux inhibiteurs de la Stéaroyl CoA désaturase (SCD) et leurs utilisations pour traiter des maladies, états et/ou troubles modulés par une enzyme Stéaroyl CoA désaturase. Les inhibiteurs de la SCD ont une certaine formule ou un sel pharmaceutiquement acceptable de celle-ci, un ester pharmaceutiquement acceptable de celle-ci, un tautomère de celle-ci, un régioisomère de celle-ci, un stéréoisomère de celle-ci, un énantiomère de celle-ci, un diastéréomère de celle-ci, un polymorphe de celle-ci ou un solvate pharmaceutiquement acceptable de celle-ci, les variables étant telles que décrites présentement.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080313&DB=EPODOC&CC=WO&NR=2008029266A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080313&DB=EPODOC&CC=WO&NR=2008029266A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LINGAM, V.S. PRASADA RAO</creatorcontrib><creatorcontrib>KHAIRATKAR-JOSHI, NEELIMA</creatorcontrib><creatorcontrib>THOMAS, ABRAHAM</creatorcontrib><creatorcontrib>CHAUDHARI, SACHIN, S</creatorcontrib><creatorcontrib>SHAH, DAISY MANISH</creatorcontrib><title>STEAROYL COA DESATURASE INHIBITORS</title><description>The present invention relates to novel Stearoyl CoA desaturase (SCD) inhibitors and uses thereof for treating diseases, conditions and/or disorders modulated by a Stearoyl CoA desaturase enzyme. The SCD inihibitors have the formula (I) or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable ester thereof, a tautomer thereof, a regioisomer thereof, a stereoisomer thereof, a enantiomer thereof, a diastereomer thereof, a polymorph thereof, or a pharmaceutically acceptable solvate thereof, wherein the variables are as described herein.
La présente invention concerne de nouveaux inhibiteurs de la Stéaroyl CoA désaturase (SCD) et leurs utilisations pour traiter des maladies, états et/ou troubles modulés par une enzyme Stéaroyl CoA désaturase. Les inhibiteurs de la SCD ont une certaine formule ou un sel pharmaceutiquement acceptable de celle-ci, un ester pharmaceutiquement acceptable de celle-ci, un tautomère de celle-ci, un régioisomère de celle-ci, un stéréoisomère de celle-ci, un énantiomère de celle-ci, un diastéréomère de celle-ci, un polymorphe de celle-ci ou un solvate pharmaceutiquement acceptable de celle-ci, les variables étant telles que décrites présentement.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAKDnF1DPKP9FFw9ndUcHENdgwJDXIMdlXw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgYGFgZGlkZmZo6GxsSpAgDUzCOR</recordid><startdate>20080313</startdate><enddate>20080313</enddate><creator>LINGAM, V.S. PRASADA RAO</creator><creator>KHAIRATKAR-JOSHI, NEELIMA</creator><creator>THOMAS, ABRAHAM</creator><creator>CHAUDHARI, SACHIN, S</creator><creator>SHAH, DAISY MANISH</creator><scope>EVB</scope></search><sort><creationdate>20080313</creationdate><title>STEAROYL COA DESATURASE INHIBITORS</title><author>LINGAM, V.S. PRASADA RAO ; KHAIRATKAR-JOSHI, NEELIMA ; THOMAS, ABRAHAM ; CHAUDHARI, SACHIN, S ; SHAH, DAISY MANISH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2008029266A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2008</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LINGAM, V.S. PRASADA RAO</creatorcontrib><creatorcontrib>KHAIRATKAR-JOSHI, NEELIMA</creatorcontrib><creatorcontrib>THOMAS, ABRAHAM</creatorcontrib><creatorcontrib>CHAUDHARI, SACHIN, S</creatorcontrib><creatorcontrib>SHAH, DAISY MANISH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LINGAM, V.S. PRASADA RAO</au><au>KHAIRATKAR-JOSHI, NEELIMA</au><au>THOMAS, ABRAHAM</au><au>CHAUDHARI, SACHIN, S</au><au>SHAH, DAISY MANISH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>STEAROYL COA DESATURASE INHIBITORS</title><date>2008-03-13</date><risdate>2008</risdate><abstract>The present invention relates to novel Stearoyl CoA desaturase (SCD) inhibitors and uses thereof for treating diseases, conditions and/or disorders modulated by a Stearoyl CoA desaturase enzyme. The SCD inihibitors have the formula (I) or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable ester thereof, a tautomer thereof, a regioisomer thereof, a stereoisomer thereof, a enantiomer thereof, a diastereomer thereof, a polymorph thereof, or a pharmaceutically acceptable solvate thereof, wherein the variables are as described herein.
La présente invention concerne de nouveaux inhibiteurs de la Stéaroyl CoA désaturase (SCD) et leurs utilisations pour traiter des maladies, états et/ou troubles modulés par une enzyme Stéaroyl CoA désaturase. Les inhibiteurs de la SCD ont une certaine formule ou un sel pharmaceutiquement acceptable de celle-ci, un ester pharmaceutiquement acceptable de celle-ci, un tautomère de celle-ci, un régioisomère de celle-ci, un stéréoisomère de celle-ci, un énantiomère de celle-ci, un diastéréomère de celle-ci, un polymorphe de celle-ci ou un solvate pharmaceutiquement acceptable de celle-ci, les variables étant telles que décrites présentement.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | STEAROYL COA DESATURASE INHIBITORS |
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