PHARMACEUTICAL COMPOSITIONS OF BUPROPION

The present invention relates to stabilized pharmaceutical compositions of bupropion or salt thereof comprising bupropion and a pharmaceutically acceptable buffering agent in an amount sufficient to attain a pH of 6 or less of the aqueous dispersion of the said composition. The present invention als...

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Hauptverfasser: JAIN, GIRISH, KUMAR, MANDAOGADE, PRASHANT, MANOHAR, CHOUGULE, MAHAVIR, BHUPAL, JOSHI, VENKATESH, MADHAVACHARYA, SRIVASTAV, SAURABH
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creator JAIN, GIRISH, KUMAR
MANDAOGADE, PRASHANT, MANOHAR
CHOUGULE, MAHAVIR, BHUPAL
JOSHI, VENKATESH, MADHAVACHARYA
SRIVASTAV, SAURABH
description The present invention relates to stabilized pharmaceutical compositions of bupropion or salt thereof comprising bupropion and a pharmaceutically acceptable buffering agent in an amount sufficient to attain a pH of 6 or less of the aqueous dispersion of the said composition. The present invention also relates to sustained release pharmaceutical compositions of bupropion or salts thereof. The sustained release pharmaceutical compositions of bupropion are prepared by melt granulation method or by non-aqueous granulation method. La présente invention concerne des compositions pharmaceutiques stabilisées de bupropion ou de sel de celui-ci comprenant du bupropion et un agent tampon pharmaceutiquement acceptable en une quantité suffisante pour que le pH de la dispersion aqueuse de cette composition n'excède pas 6. Cette invention concerne également des compositions pharmaceutiques à libération prolongée de bupropion ou de sels de celui-ci. Ces compositions pharmaceutiques à libération prolongée de bupropion sont préparées selon un procédé de granulation par fusion ou un procédé de granulation non aqueuse.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PHARMACEUTICAL COMPOSITIONS OF BUPROPION
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