SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF

The invention relates to novel substituted indoles, to the use thereof in the form of pharmacological composition substances and to use of said composition for producing medicinal preparations used for preventing and treating viral diseases, in particular caused by viruses of infectious hepatitis (H...

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Hauptverfasser: KHVAT, ALEXANDER VIKTOROVICH, MITKIN, OLEG DMITRIEVICH, IVASCHENKO, ANDREY ALEXANDROVICH, KYSIL, VOLODYMYR MIKHAILOVICH, IVASHCHENKO, ALEXANDER VASILIEVICH, TKACHENKO, SERGEY YEVGENIEVICH, SAVCHUK, NIKOLAY FILIPPOVICH, OKUN, ILYA MATUSOVICH, KYSELVEV, ALEXANDR SERGEEVICH
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creator KHVAT, ALEXANDER VIKTOROVICH
MITKIN, OLEG DMITRIEVICH
IVASCHENKO, ANDREY ALEXANDROVICH
KYSIL, VOLODYMYR MIKHAILOVICH
IVASHCHENKO, ALEXANDER VASILIEVICH
TKACHENKO, SERGEY YEVGENIEVICH
SAVCHUK, NIKOLAY FILIPPOVICH
OKUN, ILYA MATUSOVICH
KYSELVEV, ALEXANDR SERGEEVICH
description The invention relates to novel substituted indoles, to the use thereof in the form of pharmacological composition substances and to use of said composition for producing medicinal preparations used for preventing and treating viral diseases, in particular caused by viruses of infectious hepatitis (HCV, HBV), human immune deficiency (HIV), atypical pneumonia (SARS) and bird flu. The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R1 La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. Dans cette formule, R1, R1
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The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R1 La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. 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The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R1 La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. 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The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R1 La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. Dans cette formule, R1, R1</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF
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