SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF
The invention relates to novel substituted indoles, to the use thereof in the form of pharmacological composition substances and to use of said composition for producing medicinal preparations used for preventing and treating viral diseases, in particular caused by viruses of infectious hepatitis (H...
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creator | KHVAT, ALEXANDER VIKTOROVICH MITKIN, OLEG DMITRIEVICH IVASCHENKO, ANDREY ALEXANDROVICH KYSIL, VOLODYMYR MIKHAILOVICH IVASHCHENKO, ALEXANDER VASILIEVICH TKACHENKO, SERGEY YEVGENIEVICH SAVCHUK, NIKOLAY FILIPPOVICH OKUN, ILYA MATUSOVICH KYSELVEV, ALEXANDR SERGEEVICH |
description | The invention relates to novel substituted indoles, to the use thereof in the form of pharmacological composition substances and to use of said composition for producing medicinal preparations used for preventing and treating viral diseases, in particular caused by viruses of infectious hepatitis (HCV, HBV), human immune deficiency (HIV), atypical pneumonia (SARS) and bird flu. The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R1
La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. Dans cette formule, R1, R1 |
format | Patent |
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La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. Dans cette formule, R1, R1</description><language>eng ; fre ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080207&DB=EPODOC&CC=WO&NR=2007136300A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080207&DB=EPODOC&CC=WO&NR=2007136300A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KHVAT, ALEXANDER VIKTOROVICH</creatorcontrib><creatorcontrib>MITKIN, OLEG DMITRIEVICH</creatorcontrib><creatorcontrib>IVASCHENKO, ANDREY ALEXANDROVICH</creatorcontrib><creatorcontrib>KYSIL, VOLODYMYR MIKHAILOVICH</creatorcontrib><creatorcontrib>IVASHCHENKO, ALEXANDER VASILIEVICH</creatorcontrib><creatorcontrib>TKACHENKO, SERGEY YEVGENIEVICH</creatorcontrib><creatorcontrib>SAVCHUK, NIKOLAY FILIPPOVICH</creatorcontrib><creatorcontrib>OKUN, ILYA MATUSOVICH</creatorcontrib><creatorcontrib>KYSELVEV, ALEXANDR SERGEEVICH</creatorcontrib><title>SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF</title><description>The invention relates to novel substituted indoles, to the use thereof in the form of pharmacological composition substances and to use of said composition for producing medicinal preparations used for preventing and treating viral diseases, in particular caused by viruses of infectious hepatitis (HCV, HBV), human immune deficiency (HIV), atypical pneumonia (SARS) and bird flu. The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R1
La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. Dans cette formule, R1, R1</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAODnUKDvEMCQ1xdVHw9HPx93ENVnD0c1FwVPB1DfHwd1Fw8w9SCPFwVQgI8ncJdQ7x9PcDy4cGu4KEg1z93XgYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXy4v5GBgbmhsZmxgYGjsTFxqgDH8iwp</recordid><startdate>20080207</startdate><enddate>20080207</enddate><creator>KHVAT, ALEXANDER VIKTOROVICH</creator><creator>MITKIN, OLEG DMITRIEVICH</creator><creator>IVASCHENKO, ANDREY ALEXANDROVICH</creator><creator>KYSIL, VOLODYMYR MIKHAILOVICH</creator><creator>IVASHCHENKO, ALEXANDER VASILIEVICH</creator><creator>TKACHENKO, SERGEY YEVGENIEVICH</creator><creator>SAVCHUK, NIKOLAY FILIPPOVICH</creator><creator>OKUN, ILYA MATUSOVICH</creator><creator>KYSELVEV, ALEXANDR SERGEEVICH</creator><scope>EVB</scope></search><sort><creationdate>20080207</creationdate><title>SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF</title><author>KHVAT, ALEXANDER VIKTOROVICH ; MITKIN, OLEG DMITRIEVICH ; IVASCHENKO, ANDREY ALEXANDROVICH ; KYSIL, VOLODYMYR MIKHAILOVICH ; IVASHCHENKO, ALEXANDER VASILIEVICH ; TKACHENKO, SERGEY YEVGENIEVICH ; SAVCHUK, NIKOLAY FILIPPOVICH ; OKUN, ILYA MATUSOVICH ; KYSELVEV, ALEXANDR SERGEEVICH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2007136300A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; rus</language><creationdate>2008</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KHVAT, ALEXANDER VIKTOROVICH</creatorcontrib><creatorcontrib>MITKIN, OLEG DMITRIEVICH</creatorcontrib><creatorcontrib>IVASCHENKO, ANDREY ALEXANDROVICH</creatorcontrib><creatorcontrib>KYSIL, VOLODYMYR MIKHAILOVICH</creatorcontrib><creatorcontrib>IVASHCHENKO, ALEXANDER VASILIEVICH</creatorcontrib><creatorcontrib>TKACHENKO, SERGEY YEVGENIEVICH</creatorcontrib><creatorcontrib>SAVCHUK, NIKOLAY FILIPPOVICH</creatorcontrib><creatorcontrib>OKUN, ILYA MATUSOVICH</creatorcontrib><creatorcontrib>KYSELVEV, ALEXANDR SERGEEVICH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KHVAT, ALEXANDER VIKTOROVICH</au><au>MITKIN, OLEG DMITRIEVICH</au><au>IVASCHENKO, ANDREY ALEXANDROVICH</au><au>KYSIL, VOLODYMYR MIKHAILOVICH</au><au>IVASHCHENKO, ALEXANDER VASILIEVICH</au><au>TKACHENKO, SERGEY YEVGENIEVICH</au><au>SAVCHUK, NIKOLAY FILIPPOVICH</au><au>OKUN, ILYA MATUSOVICH</au><au>KYSELVEV, ALEXANDR SERGEEVICH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF</title><date>2008-02-07</date><risdate>2008</risdate><abstract>The invention relates to novel substituted indoles, to the use thereof in the form of pharmacological composition substances and to use of said composition for producing medicinal preparations used for preventing and treating viral diseases, in particular caused by viruses of infectious hepatitis (HCV, HBV), human immune deficiency (HIV), atypical pneumonia (SARS) and bird flu. The invention proposes novel substituted indoles of general formula (1) or the racemates or the optical isomers or the pharmaceutically acceptable salts and/or hydrates thereof, wherein R1, R1
La présente invention concerne de nouveaux indoles substitués, leur utilisation comme substances de compositions pharmaceutiques et l'utilisation de ces compositions pour produire des préparations médicinales destinée à la prévention et au traitement de maladies virales, en particulier causées par les virus d'hépatites infectieuses (virus de l'hépatite C, virus de l'hépatite B), le virus de l'immunodéficience humaine (VIH), la pneumonie atypique (SRAS) et la grippe aviaire. Cette invention concerne de nouveaux indoles substitués représentés par la formule (I) ou des racémates, des isomères optiques, des sels et/ou hydrates pharmaceutiquementacceptables de ceux-ci. Dans cette formule, R1, R1</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF |
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