POLYVALENT CHIMERIC OSPC VACCINOGEN AND DIAGNOSTIC ANTIGEN

A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammalian Borrelia i...

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Hauptverfasser: MARCONI, RICHARD, THOMAS, EARNHART, CHRISTOPHER
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EARNHART, CHRISTOPHER
description A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammalian Borrelia infections. L'invention concerne une protéine recombinée polyvalente chimère utile comme vaccin et pour diagnostiquer la maladie de Lyme. La protéine chimère comprend des épitopes de la région de boucle 5 et/ou la région d'hélice alpha 5 de types de protéine C de surface extérieure (OspC). Les types d'OspC sont associés à des infections de mammifères par Borrelia.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title POLYVALENT CHIMERIC OSPC VACCINOGEN AND DIAGNOSTIC ANTIGEN
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