METHODS AND DEVICES FOR SELECTING COMPOUNDS THAT INTERACT WITH IMPORTIN a 7 AND RELATED USES THEREOF

The present invention relates to methods and devices for selecting of compounds that modulate the function of importin a7, a method for producing a pharmaceutical and contraceptive composition, comprising a modulator, a respective pharmaceutical and contraceptive composition, transgenic non-human an...

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Bibliographische Detailangaben
Hauptverfasser:	SCHMIDT, TANJA, HAMPICH, FRANZISKA, HARTMANN, ENNO, BADER, MICHAEL, KOEHLER, MATTHIAS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS TESTING TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to methods and devices for selecting of compounds that modulate the function of importin a7, a method for producing a pharmaceutical and contraceptive composition, comprising a modulator, a respective pharmaceutical and contraceptive composition, transgenic non-human animals, and a method for contraception or for the treatment of a proliferative disease, breast cancer, and diabetes or a method of modifying spermatogenesis, comprising administering an effective amount of a modulator of importin a7. La présente invention concerne des procédés et dispositifs visant à sélectionner des composés modulant la fonction de l'importine a7, un procédé visant à produire une composition pharmaceutique et contraceptive, comprenant un modulateur, une composition pharmaceutique et contraceptive respective, des animaux non humains transgéniques et un procédé de contraception ou de traitement d'une maladie proliférative, du cancer du sein et du diabète, ainsi qu'un procédé de modification de la spermatogenèse, comprenant l'administration d'une quantité efficace d'un modulateur de l'importine a7.