DIPHENYL ETHER MONOAMINE REUPTAKE INHIBITOR
The present invention relates to a compound of the formula (I) wherein R1 is hydrogen or C1-C6 alkyl; X and Y are independently selected from the group consisting of fluoro, chloro and bromo; its enantiomers, racemate and mixtures of enantiomers and the pharmaceutically acceptable salts thereof, whi...
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| creator | HOWARD, HARRY, RALPH, JR |
| description | The present invention relates to a compound of the formula (I) wherein R1 is hydrogen or C1-C6 alkyl; X and Y are independently selected from the group consisting of fluoro, chloro and bromo; its enantiomers, racemate and mixtures of enantiomers and the pharmaceutically acceptable salts thereof, which exhibit activity as serotonin, norepinephrine and dopamine reuptake inhibitors, and are therefore useful in the treatment of central nervous system and other disorders.
La présente invention concerne un composé de formule (I), dans laquelle R1 est hydrogène ou alkyle C1-C6 et X et Y sont indépendamment choisis dans le groupe constitué par fluoro, chloro et bromo, ses énantiomères, un racémate et des mélanges d'énantiomères ainsi que les sels pharmaceutiquement acceptables correspondants, ces composés agissant comme inhibiteurs de la recapture de la sérotonine, de la norépinéphrine et de la dopamine, d'où leur utilité dans le traitement de troubles du système nerveux central et d'autres troubles. |
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La présente invention concerne un composé de formule (I), dans laquelle R1 est hydrogène ou alkyle C1-C6 et X et Y sont indépendamment choisis dans le groupe constitué par fluoro, chloro et bromo, ses énantiomères, un racémate et des mélanges d'énantiomères ainsi que les sels pharmaceutiquement acceptables correspondants, ces composés agissant comme inhibiteurs de la recapture de la sérotonine, de la norépinéphrine et de la dopamine, d'où leur utilité dans le traitement de troubles du système nerveux central et d'autres troubles.</description><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070405&DB=EPODOC&CC=WO&NR=2007036781A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070405&DB=EPODOC&CC=WO&NR=2007036781A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HOWARD, HARRY, RALPH, JR</creatorcontrib><title>DIPHENYL ETHER MONOAMINE REUPTAKE INHIBITOR</title><description>The present invention relates to a compound of the formula (I) wherein R1 is hydrogen or C1-C6 alkyl; X and Y are independently selected from the group consisting of fluoro, chloro and bromo; its enantiomers, racemate and mixtures of enantiomers and the pharmaceutically acceptable salts thereof, which exhibit activity as serotonin, norepinephrine and dopamine reuptake inhibitors, and are therefore useful in the treatment of central nervous system and other disorders.
La présente invention concerne un composé de formule (I), dans laquelle R1 est hydrogène ou alkyle C1-C6 et X et Y sont indépendamment choisis dans le groupe constitué par fluoro, chloro et bromo, ses énantiomères, un racémate et des mélanges d'énantiomères ainsi que les sels pharmaceutiquement acceptables correspondants, ces composés agissant comme inhibiteurs de la recapture de la sérotonine, de la norépinéphrine et de la dopamine, d'où leur utilité dans le traitement de troubles du système nerveux central et d'autres troubles.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB28QzwcPWL9FFwDfFwDVLw9ffzd_T19HNVCHINDQhx9HZV8PTz8HTyDPEP4mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgYG5gbGZuYWho6GxsSpAgAboiYH</recordid><startdate>20070405</startdate><enddate>20070405</enddate><creator>HOWARD, HARRY, RALPH, JR</creator><scope>EVB</scope></search><sort><creationdate>20070405</creationdate><title>DIPHENYL ETHER MONOAMINE REUPTAKE INHIBITOR</title><author>HOWARD, HARRY, RALPH, JR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2007036781A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2007</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HOWARD, HARRY, RALPH, JR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HOWARD, HARRY, RALPH, JR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIPHENYL ETHER MONOAMINE REUPTAKE INHIBITOR</title><date>2007-04-05</date><risdate>2007</risdate><abstract>The present invention relates to a compound of the formula (I) wherein R1 is hydrogen or C1-C6 alkyl; X and Y are independently selected from the group consisting of fluoro, chloro and bromo; its enantiomers, racemate and mixtures of enantiomers and the pharmaceutically acceptable salts thereof, which exhibit activity as serotonin, norepinephrine and dopamine reuptake inhibitors, and are therefore useful in the treatment of central nervous system and other disorders.
La présente invention concerne un composé de formule (I), dans laquelle R1 est hydrogène ou alkyle C1-C6 et X et Y sont indépendamment choisis dans le groupe constitué par fluoro, chloro et bromo, ses énantiomères, un racémate et des mélanges d'énantiomères ainsi que les sels pharmaceutiquement acceptables correspondants, ces composés agissant comme inhibiteurs de la recapture de la sérotonine, de la norépinéphrine et de la dopamine, d'où leur utilité dans le traitement de troubles du système nerveux central et d'autres troubles.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DIPHENYL ETHER MONOAMINE REUPTAKE INHIBITOR |
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