HMGCoA REDUCTASE INHIBITOR-ANGIOTENSIN CONVERTING ENZYME INHIBITOR COMPOUNDS

HMGCoA REDUCTASE INHIBITOR-ANGIOTENSIN CONVERTING ENZYME INHIBITOR COMPOUNDS

A compound that contains at least two independently active pharmacological moieties, either covalently conjoined through a physiologically labile linker or ionically associated. One pharmacological moiety is an HMGCoA reductase inhibitor (such as a statin). Another pharmacological moiety is an angio...

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Hauptverfasser: CYNKOWSKI, TADEUSZ, SMITH, THOMAS, J, CYNKOWSKA, GRAZYNA
Format: Patent
Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator CYNKOWSKI, TADEUSZ
SMITH, THOMAS, J
CYNKOWSKA, GRAZYNA
description A compound that contains at least two independently active pharmacological moieties, either covalently conjoined through a physiologically labile linker or ionically associated. One pharmacological moiety is an HMGCoA reductase inhibitor (such as a statin). Another pharmacological moiety is an angiotensin converting enzyme inhibitor. L'invention concerne un composé contenant au moins deux fractions pharmacologiques indépendamment actives, soit liées de manière covalente via un liant physiologiquement labile soit ioniquement associées. Une fraction pharmacologiquement active est un inhibiteur de la HMGCoA réductase (tel qu'une statine). L'autre fraction pharmacologiquement est un inhibiteur de l'enzyme de conversion de l'angiotensine.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title HMGCoA REDUCTASE INHIBITOR-ANGIOTENSIN CONVERTING ENZYME INHIBITOR COMPOUNDS
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