METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES
The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of d...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | THOMAS, LEO HIMMELSBACH, FRANK OHSUMI, KOJI ISHIDA, NOZOMU BARSOUMIAN, EDWARD, LEON FUJITA, KOICHI STREICHER, RUEDIGER RITTER, REGINE EICKELMANN, PETER PINNETTI, SABINE MAEZONO, KATSUMI MAIER, ROLAND DUGI, KLAUS HATANAKA, TOSHIHIRO |
| description | The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of diabetes mellitus, for reducing the weight, for preventing or treating the degeneration of pancreatic beta cells, for treating hyperinsulinemia and insulin resistance and diabetes type 1, in patients in need thereof by administering a pharmaceutical composition comprising a pyrazole-O-glycoside as defined in claim 1 , or a prodrug thereof, or a pharmaceutically acceptable salt thereof.
La présente invention concerne des méthodes permettant de prévenir ou de traiter des troubles métaboliques, d'améliorer le contrôle de la glycémie, d'empêcher la progression d'une diminution de la tolérance au glucose, d'une résistance à l'insuline et/ou d'un syndrome métabolique en diabète sucré de type 2, de prévenir ou de traiter les complications du diabète, de réduire le poids, de prévenir ou de traiter la dégénérescence des cellules bêta du pancréas, de traiter l'hyperinsulinémie, la résistance à l'insuline et le diabète de type 1 chez des patients nécessitant un tel traitement, lesquelles méthodes consistent à administrer au patient une composition pharmaceutique comprenant un pyrazole-O-glycoside tel que défini dans la revendication 1, ou un promédicament de celui-ci ou un sel pharmaceutiquement acceptable de celui-ci. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2007014895A3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2007014895A3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2007014895A33</originalsourceid><addsrcrecordid>eNrjZEjwdQ3x8HcJVnDzD1IICHINc_UL8fRzV3D0c1EICXJ1BHOAahyd_H08nRVcPIP9g1xcg4LBCvxcwxUCIoMco_x9XHX9dd19Ip39gz1dXBWAKjzDgHrDXIN5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8uL-RgYG5gaGJhaWpo7ExcaoAdA00tQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES</title><source>esp@cenet</source><creator>THOMAS, LEO ; HIMMELSBACH, FRANK ; OHSUMI, KOJI ; ISHIDA, NOZOMU ; BARSOUMIAN, EDWARD, LEON ; FUJITA, KOICHI ; STREICHER, RUEDIGER ; RITTER, REGINE ; EICKELMANN, PETER ; PINNETTI, SABINE ; MAEZONO, KATSUMI ; MAIER, ROLAND ; DUGI, KLAUS ; HATANAKA, TOSHIHIRO</creator><creatorcontrib>THOMAS, LEO ; HIMMELSBACH, FRANK ; OHSUMI, KOJI ; ISHIDA, NOZOMU ; BARSOUMIAN, EDWARD, LEON ; FUJITA, KOICHI ; STREICHER, RUEDIGER ; RITTER, REGINE ; EICKELMANN, PETER ; PINNETTI, SABINE ; MAEZONO, KATSUMI ; MAIER, ROLAND ; DUGI, KLAUS ; HATANAKA, TOSHIHIRO</creatorcontrib><description>The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of diabetes mellitus, for reducing the weight, for preventing or treating the degeneration of pancreatic beta cells, for treating hyperinsulinemia and insulin resistance and diabetes type 1, in patients in need thereof by administering a pharmaceutical composition comprising a pyrazole-O-glycoside as defined in claim 1 , or a prodrug thereof, or a pharmaceutically acceptable salt thereof.
La présente invention concerne des méthodes permettant de prévenir ou de traiter des troubles métaboliques, d'améliorer le contrôle de la glycémie, d'empêcher la progression d'une diminution de la tolérance au glucose, d'une résistance à l'insuline et/ou d'un syndrome métabolique en diabète sucré de type 2, de prévenir ou de traiter les complications du diabète, de réduire le poids, de prévenir ou de traiter la dégénérescence des cellules bêta du pancréas, de traiter l'hyperinsulinémie, la résistance à l'insuline et le diabète de type 1 chez des patients nécessitant un tel traitement, lesquelles méthodes consistent à administrer au patient une composition pharmaceutique comprenant un pyrazole-O-glycoside tel que défini dans la revendication 1, ou un promédicament de celui-ci ou un sel pharmaceutiquement acceptable de celui-ci.</description><language>eng ; fre</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>2007</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070510&DB=EPODOC&CC=WO&NR=2007014895A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20070510&DB=EPODOC&CC=WO&NR=2007014895A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>THOMAS, LEO</creatorcontrib><creatorcontrib>HIMMELSBACH, FRANK</creatorcontrib><creatorcontrib>OHSUMI, KOJI</creatorcontrib><creatorcontrib>ISHIDA, NOZOMU</creatorcontrib><creatorcontrib>BARSOUMIAN, EDWARD, LEON</creatorcontrib><creatorcontrib>FUJITA, KOICHI</creatorcontrib><creatorcontrib>STREICHER, RUEDIGER</creatorcontrib><creatorcontrib>RITTER, REGINE</creatorcontrib><creatorcontrib>EICKELMANN, PETER</creatorcontrib><creatorcontrib>PINNETTI, SABINE</creatorcontrib><creatorcontrib>MAEZONO, KATSUMI</creatorcontrib><creatorcontrib>MAIER, ROLAND</creatorcontrib><creatorcontrib>DUGI, KLAUS</creatorcontrib><creatorcontrib>HATANAKA, TOSHIHIRO</creatorcontrib><title>METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES</title><description>The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of diabetes mellitus, for reducing the weight, for preventing or treating the degeneration of pancreatic beta cells, for treating hyperinsulinemia and insulin resistance and diabetes type 1, in patients in need thereof by administering a pharmaceutical composition comprising a pyrazole-O-glycoside as defined in claim 1 , or a prodrug thereof, or a pharmaceutically acceptable salt thereof.
La présente invention concerne des méthodes permettant de prévenir ou de traiter des troubles métaboliques, d'améliorer le contrôle de la glycémie, d'empêcher la progression d'une diminution de la tolérance au glucose, d'une résistance à l'insuline et/ou d'un syndrome métabolique en diabète sucré de type 2, de prévenir ou de traiter les complications du diabète, de réduire le poids, de prévenir ou de traiter la dégénérescence des cellules bêta du pancréas, de traiter l'hyperinsulinémie, la résistance à l'insuline et le diabète de type 1 chez des patients nécessitant un tel traitement, lesquelles méthodes consistent à administrer au patient une composition pharmaceutique comprenant un pyrazole-O-glycoside tel que défini dans la revendication 1, ou un promédicament de celui-ci ou un sel pharmaceutiquement acceptable de celui-ci.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2007</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZEjwdQ3x8HcJVnDzD1IICHINc_UL8fRzV3D0c1EICXJ1BHOAahyd_H08nRVcPIP9g1xcg4LBCvxcwxUCIoMco_x9XHX9dd19Ip39gz1dXBWAKjzDgHrDXIN5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8uL-RgYG5gaGJhaWpo7ExcaoAdA00tQ</recordid><startdate>20070510</startdate><enddate>20070510</enddate><creator>THOMAS, LEO</creator><creator>HIMMELSBACH, FRANK</creator><creator>OHSUMI, KOJI</creator><creator>ISHIDA, NOZOMU</creator><creator>BARSOUMIAN, EDWARD, LEON</creator><creator>FUJITA, KOICHI</creator><creator>STREICHER, RUEDIGER</creator><creator>RITTER, REGINE</creator><creator>EICKELMANN, PETER</creator><creator>PINNETTI, SABINE</creator><creator>MAEZONO, KATSUMI</creator><creator>MAIER, ROLAND</creator><creator>DUGI, KLAUS</creator><creator>HATANAKA, TOSHIHIRO</creator><scope>EVB</scope></search><sort><creationdate>20070510</creationdate><title>METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES</title><author>THOMAS, LEO ; HIMMELSBACH, FRANK ; OHSUMI, KOJI ; ISHIDA, NOZOMU ; BARSOUMIAN, EDWARD, LEON ; FUJITA, KOICHI ; STREICHER, RUEDIGER ; RITTER, REGINE ; EICKELMANN, PETER ; PINNETTI, SABINE ; MAEZONO, KATSUMI ; MAIER, ROLAND ; DUGI, KLAUS ; HATANAKA, TOSHIHIRO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2007014895A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2007</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>THOMAS, LEO</creatorcontrib><creatorcontrib>HIMMELSBACH, FRANK</creatorcontrib><creatorcontrib>OHSUMI, KOJI</creatorcontrib><creatorcontrib>ISHIDA, NOZOMU</creatorcontrib><creatorcontrib>BARSOUMIAN, EDWARD, LEON</creatorcontrib><creatorcontrib>FUJITA, KOICHI</creatorcontrib><creatorcontrib>STREICHER, RUEDIGER</creatorcontrib><creatorcontrib>RITTER, REGINE</creatorcontrib><creatorcontrib>EICKELMANN, PETER</creatorcontrib><creatorcontrib>PINNETTI, SABINE</creatorcontrib><creatorcontrib>MAEZONO, KATSUMI</creatorcontrib><creatorcontrib>MAIER, ROLAND</creatorcontrib><creatorcontrib>DUGI, KLAUS</creatorcontrib><creatorcontrib>HATANAKA, TOSHIHIRO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>THOMAS, LEO</au><au>HIMMELSBACH, FRANK</au><au>OHSUMI, KOJI</au><au>ISHIDA, NOZOMU</au><au>BARSOUMIAN, EDWARD, LEON</au><au>FUJITA, KOICHI</au><au>STREICHER, RUEDIGER</au><au>RITTER, REGINE</au><au>EICKELMANN, PETER</au><au>PINNETTI, SABINE</au><au>MAEZONO, KATSUMI</au><au>MAIER, ROLAND</au><au>DUGI, KLAUS</au><au>HATANAKA, TOSHIHIRO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES</title><date>2007-05-10</date><risdate>2007</risdate><abstract>The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of diabetes mellitus, for reducing the weight, for preventing or treating the degeneration of pancreatic beta cells, for treating hyperinsulinemia and insulin resistance and diabetes type 1, in patients in need thereof by administering a pharmaceutical composition comprising a pyrazole-O-glycoside as defined in claim 1 , or a prodrug thereof, or a pharmaceutically acceptable salt thereof.
La présente invention concerne des méthodes permettant de prévenir ou de traiter des troubles métaboliques, d'améliorer le contrôle de la glycémie, d'empêcher la progression d'une diminution de la tolérance au glucose, d'une résistance à l'insuline et/ou d'un syndrome métabolique en diabète sucré de type 2, de prévenir ou de traiter les complications du diabète, de réduire le poids, de prévenir ou de traiter la dégénérescence des cellules bêta du pancréas, de traiter l'hyperinsulinémie, la résistance à l'insuline et le diabète de type 1 chez des patients nécessitant un tel traitement, lesquelles méthodes consistent à administrer au patient une composition pharmaceutique comprenant un pyrazole-O-glycoside tel que défini dans la revendication 1, ou un promédicament de celui-ci ou un sel pharmaceutiquement acceptable de celui-ci.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2007014895A3 |
| source | esp@cenet |
| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | METHODS FOR PREVENTING AND TREATING METABOLIC DISORDERS AND NEW PYRAZOLE-O-GLYCOSIDE DERIVATIVES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T06%3A45%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=THOMAS,%20LEO&rft.date=2007-05-10&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2007014895A3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |