PYRAZOLE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER AND AUTOIMMUNE DISORDERS

Compounds of formula (I) are inhibitors of PDK1 and CHK1 activity, and of use in the treatment of cancer and autoimmune disorders (I) : wherein R2 is a radical of formula R7-(CH2)n-, or a radical of formula -Alk-N(-R8)-R9 wherein n is 0, 1 , 2 or 3 and AIk is C1-C6 alkylene; R7 is (i) a heterocyclic...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	NORTHFIELD, CHRISTOPHER, JOHN, FROMONT, CHRISTOPHE, DRYSDALE, MARTIN, JAMES, WALMSLEY, DAVID, LEE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!