NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342,...
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| creator | PAYNE, BOBBY, JOE RANGEL, CAROLINA QIAN, NI, NANCY MASSEY, ERIN, MARIE YE, WEILAN COMBS, KATHERIN STALA, JOY WILLIS-SEVAUX, TRACY, ELLEN JUNGE, HARALD SHI, ZHENG-ZHENG VOGEL, PETER MONTGOMERY, CHUCK MCLAIN, DINA, REBECCA PHILLIPS, HEIDI SPARKS, MARY, JEAN DING, ZHIYONG JUNUTULA, JAGATH, REDDY EDWARDS, JOEL DESAUVAGE, FREDERIC GIRGIS, ROSEMARY BYERS-HORNER, ALLISON, ANNE CULBERTSON, LING, LING |
| description | The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 or PRO35250 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
La présente invention concerne des animaux transgéniques ainsi que des compositions et des procédés se rapportant à la caractérisation de la fonction génique. De manière plus spécifique, cette invention porte sur des souris transgéniques comprenant des disruptions dans les gènes PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 ou PRO35250. De telles études et caractérisations in vivo peuvent assurer une identification intéressante et la découverte de thérapies et/ou de traitements utiles dans la prévention, l'amélioration ou la correction de maladi |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2006132788A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2006132788A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2006132788A23</originalsourceid><addsrcrecordid>eNrjZHD08w9z9VFwd_VzVXDxDA4KDQjx9PcL1lFw9vcN8A_2BPMUHP1cFHxdQzz8XYIVglx9HEM8_dwVQjxcg1xD_HkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXy4v5GBgZmhsZG5hYWjkTFxqgCpWyw2</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO</title><source>esp@cenet</source><creator>PAYNE, BOBBY, JOE ; RANGEL, CAROLINA ; QIAN, NI, NANCY ; MASSEY, ERIN, MARIE ; YE, WEILAN ; COMBS, KATHERIN ; STALA, JOY ; WILLIS-SEVAUX, TRACY, ELLEN ; JUNGE, HARALD ; SHI, ZHENG-ZHENG ; VOGEL, PETER ; MONTGOMERY, CHUCK ; MCLAIN, DINA, REBECCA ; PHILLIPS, HEIDI ; SPARKS, MARY, JEAN ; DING, ZHIYONG ; JUNUTULA, JAGATH, REDDY ; EDWARDS, JOEL ; DESAUVAGE, FREDERIC ; GIRGIS, ROSEMARY ; BYERS-HORNER, ALLISON, ANNE ; CULBERTSON, LING, LING</creator><creatorcontrib>PAYNE, BOBBY, JOE ; RANGEL, CAROLINA ; QIAN, NI, NANCY ; MASSEY, ERIN, MARIE ; YE, WEILAN ; COMBS, KATHERIN ; STALA, JOY ; WILLIS-SEVAUX, TRACY, ELLEN ; JUNGE, HARALD ; SHI, ZHENG-ZHENG ; VOGEL, PETER ; MONTGOMERY, CHUCK ; MCLAIN, DINA, REBECCA ; PHILLIPS, HEIDI ; SPARKS, MARY, JEAN ; DING, ZHIYONG ; JUNUTULA, JAGATH, REDDY ; EDWARDS, JOEL ; DESAUVAGE, FREDERIC ; GIRGIS, ROSEMARY ; BYERS-HORNER, ALLISON, ANNE ; CULBERTSON, LING, LING</creatorcontrib><description>The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 or PRO35250 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
La présente invention concerne des animaux transgéniques ainsi que des compositions et des procédés se rapportant à la caractérisation de la fonction génique. De manière plus spécifique, cette invention porte sur des souris transgéniques comprenant des disruptions dans les gènes PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 ou PRO35250. De telles études et caractérisations in vivo peuvent assurer une identification intéressante et la découverte de thérapies et/ou de traitements utiles dans la prévention, l'amélioration ou la correction de maladies et de dysfonctionnements associés aux disruptions géniques telles que les troubles neurologiques; les troubles cardio-vasculaires, endothéliaux ou angiogéniques; les anomalies de l'oeil; les troubles immunologiques; les troubles oncologiques; les anomalies ou les troubles du métabolisme osseux; les troubles du métabolisme des lipides; ou les troubles de la croissance.</description><language>eng ; fre</language><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20061214&DB=EPODOC&CC=WO&NR=2006132788A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20061214&DB=EPODOC&CC=WO&NR=2006132788A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PAYNE, BOBBY, JOE</creatorcontrib><creatorcontrib>RANGEL, CAROLINA</creatorcontrib><creatorcontrib>QIAN, NI, NANCY</creatorcontrib><creatorcontrib>MASSEY, ERIN, MARIE</creatorcontrib><creatorcontrib>YE, WEILAN</creatorcontrib><creatorcontrib>COMBS, KATHERIN</creatorcontrib><creatorcontrib>STALA, JOY</creatorcontrib><creatorcontrib>WILLIS-SEVAUX, TRACY, ELLEN</creatorcontrib><creatorcontrib>JUNGE, HARALD</creatorcontrib><creatorcontrib>SHI, ZHENG-ZHENG</creatorcontrib><creatorcontrib>VOGEL, PETER</creatorcontrib><creatorcontrib>MONTGOMERY, CHUCK</creatorcontrib><creatorcontrib>MCLAIN, DINA, REBECCA</creatorcontrib><creatorcontrib>PHILLIPS, HEIDI</creatorcontrib><creatorcontrib>SPARKS, MARY, JEAN</creatorcontrib><creatorcontrib>DING, ZHIYONG</creatorcontrib><creatorcontrib>JUNUTULA, JAGATH, REDDY</creatorcontrib><creatorcontrib>EDWARDS, JOEL</creatorcontrib><creatorcontrib>DESAUVAGE, FREDERIC</creatorcontrib><creatorcontrib>GIRGIS, ROSEMARY</creatorcontrib><creatorcontrib>BYERS-HORNER, ALLISON, ANNE</creatorcontrib><creatorcontrib>CULBERTSON, LING, LING</creatorcontrib><title>NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO</title><description>The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 or PRO35250 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
La présente invention concerne des animaux transgéniques ainsi que des compositions et des procédés se rapportant à la caractérisation de la fonction génique. De manière plus spécifique, cette invention porte sur des souris transgéniques comprenant des disruptions dans les gènes PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 ou PRO35250. De telles études et caractérisations in vivo peuvent assurer une identification intéressante et la découverte de thérapies et/ou de traitements utiles dans la prévention, l'amélioration ou la correction de maladies et de dysfonctionnements associés aux disruptions géniques telles que les troubles neurologiques; les troubles cardio-vasculaires, endothéliaux ou angiogéniques; les anomalies de l'oeil; les troubles immunologiques; les troubles oncologiques; les anomalies ou les troubles du métabolisme osseux; les troubles du métabolisme des lipides; ou les troubles de la croissance.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHD08w9z9VFwd_VzVXDxDA4KDQjx9PcL1lFw9vcN8A_2BPMUHP1cFHxdQzz8XYIVglx9HEM8_dwVQjxcg1xD_HkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXy4v5GBgZmhsZG5hYWjkTFxqgCpWyw2</recordid><startdate>20061214</startdate><enddate>20061214</enddate><creator>PAYNE, BOBBY, JOE</creator><creator>RANGEL, CAROLINA</creator><creator>QIAN, NI, NANCY</creator><creator>MASSEY, ERIN, MARIE</creator><creator>YE, WEILAN</creator><creator>COMBS, KATHERIN</creator><creator>STALA, JOY</creator><creator>WILLIS-SEVAUX, TRACY, ELLEN</creator><creator>JUNGE, HARALD</creator><creator>SHI, ZHENG-ZHENG</creator><creator>VOGEL, PETER</creator><creator>MONTGOMERY, CHUCK</creator><creator>MCLAIN, DINA, REBECCA</creator><creator>PHILLIPS, HEIDI</creator><creator>SPARKS, MARY, JEAN</creator><creator>DING, ZHIYONG</creator><creator>JUNUTULA, JAGATH, REDDY</creator><creator>EDWARDS, JOEL</creator><creator>DESAUVAGE, FREDERIC</creator><creator>GIRGIS, ROSEMARY</creator><creator>BYERS-HORNER, ALLISON, ANNE</creator><creator>CULBERTSON, LING, LING</creator><scope>EVB</scope></search><sort><creationdate>20061214</creationdate><title>NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO</title><author>PAYNE, BOBBY, JOE ; RANGEL, CAROLINA ; QIAN, NI, NANCY ; MASSEY, ERIN, MARIE ; YE, WEILAN ; COMBS, KATHERIN ; STALA, JOY ; WILLIS-SEVAUX, TRACY, ELLEN ; JUNGE, HARALD ; SHI, ZHENG-ZHENG ; VOGEL, PETER ; MONTGOMERY, CHUCK ; MCLAIN, DINA, REBECCA ; PHILLIPS, HEIDI ; SPARKS, MARY, JEAN ; DING, ZHIYONG ; JUNUTULA, JAGATH, REDDY ; EDWARDS, JOEL ; DESAUVAGE, FREDERIC ; GIRGIS, ROSEMARY ; BYERS-HORNER, ALLISON, ANNE ; CULBERTSON, LING, LING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2006132788A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2006</creationdate><toplevel>online_resources</toplevel><creatorcontrib>PAYNE, BOBBY, JOE</creatorcontrib><creatorcontrib>RANGEL, CAROLINA</creatorcontrib><creatorcontrib>QIAN, NI, NANCY</creatorcontrib><creatorcontrib>MASSEY, ERIN, MARIE</creatorcontrib><creatorcontrib>YE, WEILAN</creatorcontrib><creatorcontrib>COMBS, KATHERIN</creatorcontrib><creatorcontrib>STALA, JOY</creatorcontrib><creatorcontrib>WILLIS-SEVAUX, TRACY, ELLEN</creatorcontrib><creatorcontrib>JUNGE, HARALD</creatorcontrib><creatorcontrib>SHI, ZHENG-ZHENG</creatorcontrib><creatorcontrib>VOGEL, PETER</creatorcontrib><creatorcontrib>MONTGOMERY, CHUCK</creatorcontrib><creatorcontrib>MCLAIN, DINA, REBECCA</creatorcontrib><creatorcontrib>PHILLIPS, HEIDI</creatorcontrib><creatorcontrib>SPARKS, MARY, JEAN</creatorcontrib><creatorcontrib>DING, ZHIYONG</creatorcontrib><creatorcontrib>JUNUTULA, JAGATH, REDDY</creatorcontrib><creatorcontrib>EDWARDS, JOEL</creatorcontrib><creatorcontrib>DESAUVAGE, FREDERIC</creatorcontrib><creatorcontrib>GIRGIS, ROSEMARY</creatorcontrib><creatorcontrib>BYERS-HORNER, ALLISON, ANNE</creatorcontrib><creatorcontrib>CULBERTSON, LING, LING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PAYNE, BOBBY, JOE</au><au>RANGEL, CAROLINA</au><au>QIAN, NI, NANCY</au><au>MASSEY, ERIN, MARIE</au><au>YE, WEILAN</au><au>COMBS, KATHERIN</au><au>STALA, JOY</au><au>WILLIS-SEVAUX, TRACY, ELLEN</au><au>JUNGE, HARALD</au><au>SHI, ZHENG-ZHENG</au><au>VOGEL, PETER</au><au>MONTGOMERY, CHUCK</au><au>MCLAIN, DINA, REBECCA</au><au>PHILLIPS, HEIDI</au><au>SPARKS, MARY, JEAN</au><au>DING, ZHIYONG</au><au>JUNUTULA, JAGATH, REDDY</au><au>EDWARDS, JOEL</au><au>DESAUVAGE, FREDERIC</au><au>GIRGIS, ROSEMARY</au><au>BYERS-HORNER, ALLISON, ANNE</au><au>CULBERTSON, LING, LING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO</title><date>2006-12-14</date><risdate>2006</risdate><abstract>The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 or PRO35250 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
La présente invention concerne des animaux transgéniques ainsi que des compositions et des procédés se rapportant à la caractérisation de la fonction génique. De manière plus spécifique, cette invention porte sur des souris transgéniques comprenant des disruptions dans les gènes PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 ou PRO35250. De telles études et caractérisations in vivo peuvent assurer une identification intéressante et la découverte de thérapies et/ou de traitements utiles dans la prévention, l'amélioration ou la correction de maladies et de dysfonctionnements associés aux disruptions géniques telles que les troubles neurologiques; les troubles cardio-vasculaires, endothéliaux ou angiogéniques; les anomalies de l'oeil; les troubles immunologiques; les troubles oncologiques; les anomalies ou les troubles du métabolisme osseux; les troubles du métabolisme des lipides; ou les troubles de la croissance.</abstract><oa>free_for_read</oa></addata></record> |
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| title | NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO |
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