A PROCESS FOR PREPARING (2R,3S)-1,2-EPOXY-3-(PROTECTED)AMINO-4-SUBSTITUTED BUTANE AND INTERMEDIATES THEREOF

The present invention relates to a process for preparing (2R,3S)-1-halo-2-hydroxy-3-(protected)amino-4-substituted butane comprising contacting a mutagenized Rhodococcus erythropolis having ATCC deposit no. PTA-6648 with (3S)-1-halo-2-oxo-3-(protected)amino-4-substituted butane substrate. The presen...

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Hauptverfasser: CHIANG, SHU-JEN, STEIN, GREGORY, L, YOU, LI, ANDERSON, WENDY, L, XING, ZIZHUO, BOWERS, NIGEL, IAN, FRANCESCHINI, THOMAS, SKONEZNY, PAUL, M
Format: Patent
Sprache:eng ; fre
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