HYDROPHILIC DISPERSIONS OF NANOPARTICLES OF INCLUSION COMPLEXES OF MACROMOLECULES

The present invention provides hydrophilic dispersions comprising nanoparticles of inclusion complexes consisting essentially of nanosized particles of a macromolecule wrapped in an amphiphilic polymer such that non-valent bonds are formed between the macromolecule and the amphiphilic polymer. The m...

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Hauptverfasser: GOLDSHTEIN, RINA, GITIS, LARISA, TULBOVITZ, BORIS, RATNER, GALINA
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creator GOLDSHTEIN, RINA
GITIS, LARISA
TULBOVITZ, BORIS
RATNER, GALINA
description The present invention provides hydrophilic dispersions comprising nanoparticles of inclusion complexes consisting essentially of nanosized particles of a macromolecule wrapped in an amphiphilic polymer such that non-valent bonds are formed between the macromolecule and the amphiphilic polymer. The macromolecule may be a naturally-occurring, synthetic or recombinant polypeptide, protein, polysaccharide or polynucleotide, and the amphiphilic polymer is a polysaccharide or a modified polysaccharide such as starch, chitosan or an alginate. Dispersions hydrophiles comprenant des nanoparticules de complexes d'inclusion constituées de essentiellement de nanoparticules d'une macromolécule enveloppée dans un polymère amphiphile de sorte que des liaisons non valentes s'établissent entre la macromolécule et le polymère amphiphile. La macromolécule peut être constituée par un polypeptide, une protéine, un polysaccharide ou un polynucléotide naturel, de synthèse ou de recombinaison, et le polymère amphiphile peut être constitué par un polysaccharide ou un polysaccharide modifié tel que de l'amidon, du chitosane ou un complexe d'inclusion d'alginate.
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subjects CHEMISTRY
DERIVATIVES THEREOF
FODDER
FOODS OR FOODSTUFFS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title HYDROPHILIC DISPERSIONS OF NANOPARTICLES OF INCLUSION COMPLEXES OF MACROMOLECULES
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