4-PIPERAZINYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) wherein A1 , A2, A3, A4, A5, A6, A7, A8, X4, X6, R2k, R2I, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical...

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Hauptverfasser:	ENNIS, MICHAEL, DALTON, KORTUM, STEVEN, WADE, TENBRINK, RUTH, ELIZABETH
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) wherein A1 , A2, A3, A4, A5, A6, A7, A8, X4, X6, R2k, R2I, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed. L'invention concerne des composés et des sels pharmaceutiquement acceptables, les composés ayant une structure représentée par la formule (I) dans laquelle A1 , A2, A3, A4, A5, A6, A7, A8, X4, X6, R2k, R2I, R4, R5, et R6 sont tels que définis dans la description de l'invention. L'invention concerne également des compositions pharmaceutiques correspondantes, des procédés de traitement, des procédés de synthèse et des intermédiaires.