QUINAZOLINONE T-TYPE CALCIUM CHANNEL ANTAGONISTS

The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions co...

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Hauptverfasser: YOUNG, STEVEN, D, NGO, PHUNG LE, BARROW, JAMES, C, RITTLE, KENNETH, E, CUBE, ROWENA, V, YANG, ZHIQIANG
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creator YOUNG, STEVEN, D
NGO, PHUNG LE
BARROW, JAMES, C
RITTLE, KENNETH, E
CUBE, ROWENA, V
YANG, ZHIQIANG
description The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved. L'invention concerne des composés de quinazolinone qui sont des antagonistes de canaux calciques de type T, et qui sont utilisés pour traiter ou prévenir des troubles ou des maladies dans lesquels les canaux calciques de type T sont impliqués. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés, et l'utilisation de ces composés et compositions pour prévenir ou traiter des maladies dans lesquelles les canaux calciques de type T sont impliqués.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title QUINAZOLINONE T-TYPE CALCIUM CHANNEL ANTAGONISTS
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