METHOD FOR MANUFACTURING 4-HYDROXY-L-ISOLEUCINE OR A SALT THEREOF

METHOD FOR MANUFACTURING 4-HYDROXY-L-ISOLEUCINE OR A SALT THEREOF

Present invention provides a method for manufacturing 4-hydroxy-L-isoleucine. A method for manufacturing 4-hydroxy-L-isoleucine or a salt thereof, characterized by comprising the steps of contacting the biocatalyst having activity in catalyzing a reaction producing 4-hydroxy-L-isoleucine from acetal...

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Hauptverfasser: MATSUI, KAZUHIKO, NIO, NORIKI, WAKABAYASHI, HIDEHIKO, KODERA, TOMOHIRO, SMIRNOV, SERGEY, VASILIEVICH, RUSHKEVICH, NATALIA, YURIEVNA, NOVIKOVA, ANNA, EVGENIEVNA, RAKITINA, VALERIYA, AVTANDILOVNA, PTITSYN, LEONID, ROMANOVICH, MATROSOV, NIKOLAY, GEORGIEVICH, SAMSONOVA, NATALIA, NIKOLAEVNA
Format: Patent
Sprache:eng ; fre
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Present invention provides a method for manufacturing 4-hydroxy-L-isoleucine. A method for manufacturing 4-hydroxy-L-isoleucine or a salt thereof, characterized by comprising the steps of contacting the biocatalyst having activity in catalyzing a reaction producing 4-hydroxy-L-isoleucine from acetaldehyde and a-ketobutyric acid or a salt thereof in the presence of an amino group donor with acetaldehyde and a-ketobutyric acid or a salt thereof in the presence of an amino group donor, and producing 4-hydroxy-L-isoleucine L'invention concerne un procédé de préparation de 4-hydroxy-L-isoleucine, caractérisé par les étapes consistant à mettre en contact un biocatalyseur produisant un effet catalyseur sur la réaction permettant la production de 4-hydroxy-L-isoleucine à partir d'acétaldehyde et d'un acide cétobutyrique ou d'un sel de celui-ci, en présence d'un donneur de groupe aminé, avec un acétaldéhyde et un acide a-cétobutyrique ou un sel de celui-ci, en présence d'un donneur de groupe aminé, et à produire de la 4-hydroxy-L-isoleucine.